Results 101 to 110 of about 538,877 (298)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Self-powered ferroelectric photodetectors offer an attractive platform for low-power optoelectronics, exploiting intrinsic bulk photovoltaic effects to achieve bias-free operation.
Jabir Zamir Minhas +5 more
doaj +1 more source
On entropy, entropy-like quantities, and applications
35 pages, no figures.
Amigó, José +2 more
openaire +3 more sources
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Lightweight self-powered digital aircraft rotational speed sensor up to 10,000 rpm
The low-altitude transport has demonstrated significant growth potential driven by rapid advancements in unmanned aerial vehicles (UAVs) technology. Herein, rotor UAVs are increasingly favored by consumers due to their unique advantages.
Yuejuan Li +11 more
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Entropy of Quantum Measurement [PDF]
A notion of entropy of a normal state on a finite von Neumann algebra in Segal’s sense is considered, and its superadditivity is proven together with a necessary and sufficient condition for its additivity.
Podsędkowska, Hanna
core
Black hole entropy and entropy of entanglement [PDF]
22 pages, 2 figures, uses harvmac and epsf fixed three minor sign errors, improved the writing in ...
openaire +3 more sources
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source

