Results 101 to 110 of about 538,877 (298)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Drift-free ferroelectric photodetection with fast temporal response via thermal diffusion engineering

open access: yesNature Communications
Self-powered ferroelectric photodetectors offer an attractive platform for low-power optoelectronics, exploiting intrinsic bulk photovoltaic effects to achieve bias-free operation.
Jabir Zamir Minhas   +5 more
doaj   +1 more source

On entropy, entropy-like quantities, and applications

open access: yesDiscrete and Continuous Dynamical Systems - B, 2015
35 pages, no figures.
Amigó, José   +2 more
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Lightweight self-powered digital aircraft rotational speed sensor up to 10,000 rpm

open access: yesNano Research
The low-altitude transport has demonstrated significant growth potential driven by rapid advancements in unmanned aerial vehicles (UAVs) technology. Herein, rotor UAVs are increasingly favored by consumers due to their unique advantages.
Yuejuan Li   +11 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Entropy of Quantum Measurement [PDF]

open access: yes, 2015
A notion of entropy of a normal state on a finite von Neumann algebra in Segal’s sense is considered, and its superadditivity is proven together with a necessary and sufficient condition for its additivity.
Podsędkowska, Hanna
core  

Black hole entropy and entropy of entanglement [PDF]

open access: yesNuclear Physics B, 1995
22 pages, 2 figures, uses harvmac and epsf fixed three minor sign errors, improved the writing in ...
openaire   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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