Results 111 to 120 of about 255,733 (268)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

From barcode entropy to metric entropy

open access: yesJournal of Fixed Point Theory and Applications
18 ...
Cineli, Erman   +2 more
openaire   +2 more sources

Preparation of Tunable Cu−Ag Nanostructures by Electrodeposition in a Deep Eutectic Solvent

open access: yesChemElectroChem
The green transition requires new, clean, inexpensive, and sustainable strategies to prepare controllable bimetallic and multimetallic nanostructures. Cu−Ag nanostructures, for example, are promising bimetallic catalysts for different electrocatalytic ...
Elena Plaza‐Mayoral   +5 more
doaj   +1 more source

Strain-enhanced image recognition via piezo-phototronic effect in MnSe/α-In2Se3 heterostructure photodetector

open access: yesNano Research
The discovery of two-dimensional (2D) van der Waals materials has created unprecedented opportunities for flexible optoelectronics and bio-inspired neuromorphic systems. Here, we present a flexible broadband MnSe/α-In2Se3 p–n heterojunction photodetector
Shidai Tian   +9 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Self‐Powered Clamp‐On Pyroelectric Tactile Sensor for Intelligent Recognition of Film Materials

open access: yesSusMat
Tactile sensors are a potential solution for material identification. However, current potential tactile sensors for material identification are pressed, expensive, and applications‐confined. Here we report a clamped‐on pyroelectric tactile sensor on the
Shengjie Yin   +5 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Smart Surface of Steering Wheel Based on Triboelectric Nanogenerator and Artificial Intelligence in Driving Monitoring System

open access: yesNanomaterials
Real-time driving monitoring systems can use self-powered sensors based on artificial intelligence (AI) and triboelectric nanogenerators (TENGs). Here, we created a TENG-based self-powered intelligent steering wheel that can detect hand gripping.
Fengguang Fan   +9 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy