Results 131 to 140 of about 538,877 (298)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

MELE: MAXIMUM ENTROPY LEUVEN ESTIMATORS [PDF]

open access: yes
Multicollinearity hampers empirical econometrics. The remedies proposed to date suffer from pitfalls of their own. The ridge estimator is not generally accepted as a vital alternative to the ordinary least-squares (OLS) estimator because it depends upon ...
Paris, Quirino
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Investigate on dissimilar welding of high-entropy alloy and 310S with various fillers

open access: yesMaterials & Design
This study investigates the microstructure and mechanical properties of non-equimolar CoCrFeMoNi high-entropy alloy (HEA) and SUS310S stainless steel dissimilar welds using different filler materials.
Chihhsien Liao   +6 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Probing contact electrification processes from interfacial charge transfer to bulk transport in semicrystalline polymers

open access: yesNature Communications
Contact electrification (CE), a ubiquitous phenomenon enabling mechanical-driven power generation, has emerged as a promising approach for sustainable energy conversion.
Kai Dong   +4 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Preparation of Tunable Cu−Ag Nanostructures by Electrodeposition in a Deep Eutectic Solvent

open access: yesChemElectroChem
The green transition requires new, clean, inexpensive, and sustainable strategies to prepare controllable bimetallic and multimetallic nanostructures. Cu−Ag nanostructures, for example, are promising bimetallic catalysts for different electrocatalytic ...
Elena Plaza‐Mayoral   +5 more
doaj   +1 more source

Strain-enhanced image recognition via piezo-phototronic effect in MnSe/α-In2Se3 heterostructure photodetector

open access: yesNano Research
The discovery of two-dimensional (2D) van der Waals materials has created unprecedented opportunities for flexible optoelectronics and bio-inspired neuromorphic systems. Here, we present a flexible broadband MnSe/α-In2Se3 p–n heterojunction photodetector
Shidai Tian   +9 more
doaj   +1 more source

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