Results 71 to 80 of about 26,272 (260)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

A New Perspective on Improving the Lossless Compression Efficiency for Initially Acquired Images

open access: yesIEEE Access, 2019
A new lossless compression scheme of compressing the initially-acquired continuous-intensity images with a lossy compression algorithm to obtain higher compression efficiency is proposed. Even if a lossy algorithm is employed, for decoded original images,
Jianyu Lin
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Entropy of Closure Operators and Network Coding Solvability

open access: yesEntropy, 2014
The entropy of a closure operator has been recently proposed for the study of network coding and secret sharing. In this paper, we study closure operators in relation to their entropy. We first introduce four different kinds of rank functions for a given
Maximilien Gadouleau
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Improved entropy encoding for high efficient video coding standard

open access: yesAlexandria Engineering Journal, 2018
The High Efficiency Video Coding (HEVC) has better coding efficiency, but the encoding performance has to be improved to meet the growing multimedia applications.
B.S. Sunil Kumar   +2 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Joint Source-Channel Polarization With Side Information

open access: yesIEEE Access, 2018
As an extension of source polarization and channel polarization, this paper considers joint source-channel polarization, which results in a joint source-channel coding (JSCC) scheme using a quasiuniform systematic polar code (SPC).
Liqiang Jin, Hongwen Yang
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

On a coding theorem connected with Rényi's entropy

open access: yesInformation and Control, 1975
A new measure L(α), called average code length of order α, has been defined and its relationship with Rényi's entropy has been discussed. Using L(α), a coding theorem for discrete noiseless channels has been proved.
openaire   +2 more sources

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