Results 61 to 70 of about 26,272 (260)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Coding By Quantum Entanglement Entropy

open access: yesInternational Journal of Nanotechnology in Medicine & Engineering, 2017
In our view, the Universe can be described as having two forms of energy: one related to attractive gravitational forces, which is negative, and the other related to mass according to Einstein’s formula E = mc2, which is positive. The generation of nonequilibrium structures (such as Benard vortices or chemical oscillations), where energy is conserved ...
openaire   +1 more source

Chains, entropy, coding [PDF]

open access: yesErgodic Theory and Dynamical Systems, 1986
AbstractVarious definitions of the entropy for countable-state topological Markov chains are considered. Concrete examples show that these quantities do not coincide in general and can behave badly under nice maps. Certain restricted random walks which arise in a problem in magnetic recording provide interesting examples of chains.
openaire   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Adaptive Video Transmission Using Residue Octree Cubes

open access: yesComputers, 2014
This paper proposes a method of transmitting video streaming data based on downsampling-upsampling pyramidal decomposition. By implementing an octal tree decomposition of the frame cubes, prior to transforming them into hypercubes, the algorithm manages ...
Adrian Enache, Costin-Anton Boiangiu
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Kernel technologies and applications of AVS2 video coding standard

open access: yesDianxin kexue, 2017
A brief introduction was given to the development history of AVS video coding standards.Then an overview of the key technologies adopted in AVS2 video coding standard (GB/T 33475.2-2016) was provided,including flexible prediction partition,multiple ...
Siwei MA, Falei LUO, Tiejun HUANG
doaj  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

HENCE: Hardware End-to-End Neural Conditional Entropy Encoder for Lossless 3D Medical Image Compression

open access: yesIEEE Access
Recently, learning-based lossless compression methods for volumetric medical images have attracted much attention. They can achieve higher compression ratios than traditional methods, albeit at the cost of slower compression speed.
Jietao Chen   +5 more
doaj   +1 more source

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