Results 161 to 170 of about 4,290,745 (350)

Numerical analysis of entropy generation in mixed convection flow with viscous dissipation effects in vertical channel

open access: yes, 2012
[[abstract]]A numerical investigation is performed into the entropy generated within a mixed convection flow with viscous dissipation effects in a parallel-plate vertical channel. In performing the analysis, it is assumed that the flow within the channel
Chen, Cha'o-Kuang; Lai, Hsin-Yi ; Liu, Chin-Chia
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

a cross-entropy based multiagent approach for multiclass activity chain modeling and simulation [PDF]

open access: yes
This paper attempts to model complex destination-chain, departure time and route choices based on activity plan implementation and proposes an arc-based cross entropy method for solving approximately the dynamic user equilibrium in multiagent-based ...
Jean-Patrick Lebacque, Tai-Yu Ma
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

The computational model of nanofluid considering heat transfer and entropy generation across a curved and flat surface. [PDF]

open access: yesSci Rep, 2023
Alharbi SO   +6 more
europepmc   +1 more source

Specific Entropy Generation in a Gas Turbine Power Cycle

open access: yes, 2017
Numerous studies have shown that the minimization of entropy generation does not always lead to an optimum performance in energy conversion systems. The equivalence between minimum entropy generation and maximum power output or maximum thermal efficiency
Y. Haseli
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

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