Results 101 to 110 of about 268,561 (292)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
, 2015 The mutual information between stimulus and spike-train response is commonly used to monitor neural coding efficiency, but neuronal computation broadly conceived requires more refined and targeted information measures of input-output joint processes.
Crutchfield, James P. +2 more
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Mixed Convection and Entropy Generation of an Ag-Water Nanofluid in an Inclined L-Shaped Channel
Energies, 2019 This paper investigates the mixed convection and entropy generation of an Ag-water nanofluid in an L-shaped channel fixed at an inclination angle of 30° to the horizontal axis.
Taher Armaghani +3 more
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Entropy Generation in Laminar Fluid Flow through a Circular Pipe
Entropy, 2003 : A numerical solution to the entropy generation in a circular pipe is made. Radial and axial variations are considered. Navier-Stokes equations in cylindrical coordinates are used to solve the velocity and temperature fields.
Rached Ben-Mansour, Ahmet Z. Sahin
doaj +1 more source
Maximization of Extractable Randomness in a Quantum Random-Number Generator
, 2015 The generation of random numbers via quantum processes is an efficient and reliable method to obtain true indeterministic random numbers that are of vital importance to cryptographic communication and large-scale computer modeling.
Assad, S. M. +6 more
core +1 more source
Entropy Rates of the Multidimensional Moran Processes and Generalizations
, 2014 The interrelationships of the fundamental biological processes natural selection, mutation, and stochastic drift are quantified by the entropy rate of Moran processes with mutation, measuring the long-run variation of a Markov process. The entropy rate is shown to behave intuitively with respect to evolutionary parameters such as monotonicity with ...
openaire +2 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Numerical Heat Transfer Analysis of Evacuated Tube Solar Collector Using MXene/Soyabean Oil Nanofluid [PDF]
E3S Web of ConferencesThis study focuses on investigating the thermo-hydraulic performance and entropy generation rate of an evacuated tube solar collector using MXene/Soybean oil as a working nanofluid by means of Computational Fluid Dynamics (CFD).
Awis Nur Amirah +4 more
doaj +1 more source