Results 121 to 130 of about 280,377 (325)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
On the Entropy Production Due to Explosion in Seawater [PDF]
, 2005 Ram Prasad Yadav +2 more
openalex +1 more source
Work, entropy production, and thermodynamics of information under\n protocol constraints [PDF]
, 2020 Artemy Kolchinsky, David H. Wolpert
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Thermodynamic Hamiltonian and Entropy Production
MathematicsThe variational method holds considerable significance within mathematical and theoretical physics. Its importance stems from its capacity to characterise natural systems through physical quantities, irrespective of the chosen frame of reference.
Umberto Lucia, Giulia Grisolia
doaj +1 more source
Entropy Production during Reheating at Late Times and Neutrino Decoupling [PDF]
, 2002 Paramita Adhya, Dwaipayan Chaudhuri
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Between Waves and Diffusion: Paradoxical Entropy Production in an Exceptional Regime
Entropy, 2018 The entropy production rate is a well established measure for the extent of irreversibility in a process. For irreversible processes, one thus usually expects that the entropy production rate approaches zero in the reversible limit.
Karl Heinz Hoffmann +3 more
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The Character of Entropy Production in Rayleigh–Bénard Convection
Entropy, 2014 In this study; the Rayleigh–Bénard convection model was established; and a great number of Bénard cells with different numbered vortexes were acquired by numerical simulation.
Chenxia Jia, Chengjun Jing, Jian Liu
doaj +1 more source