Results 71 to 80 of about 281,198 (279)

Saturation of entropy production in quantum many-body systems

open access: yes, 2017
Bridging the second law of thermodynamics and microscopic reversible dynamics has been a longstanding problem in statistical physics. We here address this problem on the basis of quantum many-body physics, and discuss how the entropy production saturates
Iyoda, Eiki   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Entropy current and entropy production in relativistic spin hydrodynamics

open access: yesPhysics Letters B
We use a first-principle quantum-statistical method to derive the expression of the entropy production rate in relativistic spin hydrodynamics. We show that the entropy current is not uniquely defined and can be changed by means of entropy-gauge ...
Francesco Becattini   +2 more
doaj   +1 more source

On Entropic Framework Based on Standard and Fractional Phonon Boltzmann Transport Equations

open access: yesEntropy, 2019
Generalized expressions of the entropy and related concepts in non-Fourier heat conduction have attracted increasing attention in recent years. Based on standard and fractional phonon Boltzmann transport equations (BTEs), we study entropic functionals ...
Shu-Nan Li, Bing-Yang Cao
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Entropy Production in the Theory of Heat Conduction in Solids

open access: yesEntropy, 2016
The evolution of the entropy production in solids due to heat transfer is usually associated with the Prigogine’s minimum entropy production principle.
Federico Zullo
doaj   +1 more source

Quantum jumps and entropy production

open access: yes, 2003
The irreversible motion of an open quantum system can be represented through an ensemble of state vectors following a stochastic dynamics with piecewise deterministic paths.
Breuer, Heinz-Peter
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Generalized Entropy Production in Collisionless Plasma Flows and Turbulence

open access: yesPhysical Review X, 2022
Collisionless plasmas exhibit nonthermal and anisotropic particle distributions after being energized; as a consequence, they enter a state of low Boltzmann-Gibbs (BG) entropy relative to the thermal state.
Vladimir Zhdankin
doaj   +1 more source

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