Results 81 to 90 of about 2,530,373 (308)
Internet skills of medical faculty and students: is there a difference?
BMC Medical Education, 2019 Background The shift from a more didactic to student-centred pedagogical approach has led to the implementation of new information communication technology (ICT) innovations and curricula.
Diane O’Doherty +6 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The market entry paradox [PDF]
This paper discusses a simultaneous market entry game between two firms with different fixed costs. This case is a typical application of mixed strategy equilibria.
Stähler, Frank
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Managerial incentives and social efficiency of entry [PDF]
This paper studies the role of separation of ownership and management in determining the welfare implications of entry in oligopolistic markets. We show, in the presence of managerial incentive schemes with cost asymmetry, that entry is socially ...
Yingyi Tsai, Arijit Mukherjee
core
A Simple and Green Protocol for 2H-Indazolo[2,1-b]phthalazine-triones Using Grinding Method
Journal of Chemistry, 2013 A robust, facile, and solvent-free route for the three-component synthesis of 2H-indazolo[2,1-b]phthalazine-triones in the presence of a catalytic amount of p-toluene sulfonic acid utilizing grinding has been developed.
Xiao-chuan Jia +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Do Entry Conditions Vary over Time? Entry and Competition in the Broadband Market: 1999-2003 [PDF]
We extend Bresnahan and Reiss’s (1991) model of local oligopoly to allow firm entry and exit over time. In our framework, entrants have to incur sunk costs in order to enter a market.
Orazem, Peter, Xiao, Mo
core
Zeitschrift für Kristallographie - New Crystal Structures, 2013 C24H20AgF3N8O7S2, monoclinic, C2/c (no. 15), a = 31.864(5) Å, b = 6.7191(10) Å, c = 14.052(2) Å, β = 97.006(3)°, V = 2986.0 Å3, Z = 4, Rgt(F) = 0.0606, wRref(F2) = 0.1637, T = 293 K.
Li Jing +4 more
doaj +1 more source