Results 121 to 130 of about 391,750 (316)

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Prime Strictly Concentric Magic Squares of Odd Order

open access: yesMathematics
Magic squares have been widely studied, with publications of mathematical interest dating back over 100 years. Most studies construct and analyse specific subsets of magic squares, with some exploring links to puzzles, number theory, and graph theory ...
Anna Louise Skelt   +2 more
doaj   +1 more source

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

open access: yesFEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai   +2 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Invisiblizing Trans Homelessness: The Prefiguration of Cis Homelessness through Homelessness Counts

open access: yesAtlantis
Municipalities in Canada routinely count unhoused populations to inform policy and services. By examining 165 English Canadian municipal homeless count reports, this article explores how trans, Two Spirit, and nonbinary (T2SNB) people, and sex and gender
A.J. Withers
doaj  

Improved resolution in extracellular vesicle populations using 405 instead of 488 nm side scatter

open access: yesJournal of Extracellular Vesicles, 2018
Improvements in identification and assessment of extracellular vesicles (EVs) have fuelled a recent surge in EV publications investigating their roles as biomarkers and mediators of disease.
Mark J. McVey   +2 more
doaj   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

Methods currently applied to study the prevalence of Clostridioides difficile in foods

open access: yesAIMS Agriculture and Food, 2020
Clostridioides difficile is responsible for most cases of antibiotic- and hospital-associated diarrhoea. Several studies have demonstrated the presence of C.
Joana Barbosa   +2 more
doaj   +1 more source

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