Results 141 to 150 of about 396,999 (317)
Invisiblizing Trans Homelessness: The Prefiguration of Cis Homelessness through Homelessness Counts
Municipalities in Canada routinely count unhoused populations to inform policy and services. By examining 165 English Canadian municipal homeless count reports, this article explores how trans, Two Spirit, and nonbinary (T2SNB) people, and sex and gender
A.J. Withers
doaj
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
The Measurement of Proliferation in Tissue Cultures by Enumeration of Cell Nuclei [PDF]
Katherine K. Sanford +4 more
openalex +1 more source
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
TWO RECURSIVELY ENUMERABLE SETS OF INCOMPARABLE DEGREES OF UNSOLVABILITY (SOLUTION OF POST'S PROBLEM, 1944) [PDF]
R. Friedberg
openalex +1 more source
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Prime Strictly Concentric Magic Squares of Odd Order
Magic squares have been widely studied, with publications of mathematical interest dating back over 100 years. Most studies construct and analyse specific subsets of magic squares, with some exploring links to puzzles, number theory, and graph theory ...
Anna Louise Skelt +2 more
doaj +1 more source
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Preliminary enumeration of the lichens of Lancaster County, Pennsylvania
Amos Arthur Heller
openalex +2 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source

