Results 161 to 170 of about 407,965 (310)

Reverse engineering molecules from fingerprints through deterministic enumeration and generative models. [PDF]

J Cheminform
Meyer P, Duigou T, Gricourt G, Faulon JL.   +3 more
europepmc   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Can Mimosa pudica Plants Enumerate Light Exposure Events? [PDF]

Cogn Sci
Vishton PM, Bartosh PJ.
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A geo-enabled digital tool for microplanning and delivery of indoor residual spray in Zambia: A case study, 2016-2020. [PDF]

PLOS Glob Public Health
Martin AC, Bwalya F, Riley C, Pollard D, Mumba K, Hamainza B, Silumbe K, Larsen DA, Winters B, Chirwa B, Bridges DJ, Winters A.   +11 more
europepmc   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis. [PDF]

Mol Oncol
De Meo M, Siringo M, Vici A, Zeuner A, Gandini O, Gazzaniga P, Nicolazzo C.   +6 more
europepmc   +1 more source

Development of a 16S-23S rRNA intergenic spacer-based quantitative PCR assay for improved detection and enumeration ofLactococcus garvieae [PDF]

, 2012
Hien Dang, Hee Kuk Park, Wonyong Kim, Hyoung‐Shik Shin   +3 more
openalex   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Two-stage cluster sampling to assess SARS-CoV-2 seroprevalence without pre-enumeration: An example from Madagascar. [PDF]

PLoS One
Lorenz E, Amuasi J, Randrianarisoa T, Rasamoelina T, Gunga L, Benke D, Ströbele J, Kettenbeil J, Loag W, Andriamahandry H, Razanakolona L, Randrianirina JR, Randrianasolo H, Ratombotsoa JC, Nahita F, Eibach D, Fusco D, May J, Rakotoarivelo RA, Souares A, Bonnet E, Struck NS.   +21 more
europepmc   +1 more source