Results 231 to 240 of about 307,376 (353)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Enumeration of Microscopic Ovarian Structures in Rodents: Best Practices and Toxicological Significance. [PDF]

Birth Defects Res
Coder PS, Vidal JD, Picut CA, Dray BK, Baily J, de Rijk E, Zimmerman B.   +6 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

CellSearch-based isolation of circulating tumor cells from ascitic fluid enables molecular characterization of ovarian cancer. [PDF]

J Liq Biopsy
Gorini F, Maloberti T, Coschina E, Mezzapesa F, Petrovic B, Gallerani G, Ferracin M, Scarpelli E, De Leo A, Kurelac I, De Iaco P, Angelini S, Perrone AM, de Biase D, Ravegnini G.   +14 more
europepmc   +1 more source

Enumerating semifields

Electronic Notes in Discrete Mathematics, 2013
openaire   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Spoilage-Associated Bacteria in Fresh Cow Cheeses: Diversity, Spoilage-Related Changes, Quantification and Identification Approaches-A Scoping Review. [PDF]

Microorganisms
Anchundia M, Santacruz S.
europepmc   +1 more source

Scalable subgraph enumeration in MapReduce: a cost-oriented approach

The VLDB journal, 2015
Longbin Lai, Lu Qin, Xue-Min Lin, Lijun Chang   +3 more
semanticscholar   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Improvements in chemical reaction pathway exploration algorithms and dataset generation. [PDF]

Sci Data
Dong Z, Zhang H, Li B, Mi S, Yin J, Wang J, Ma J, Zhu T.   +7 more
europepmc   +1 more source