Results 31 to 40 of about 7,644 (156)
N‐Acetylglucosamine Selectively Attenuates Neuroinflammation in a Mouse Model of Mitochondrial Dysfunction
Acta Physiologica, Volume 242, Issue 3, March 2026.ABSTRACT Aim
Mitochondrial dysfunction plays a central role in multiple neurodegenerative diseases, yet the temporal sequence of cellular events underlying neurodegeneration remains poorly defined. This study aimed to characterize the progression of neurodegeneration in a mouse model of fatal mitochondrial encephalopathy and to evaluate the therapeutic Laura Jiménez‐Sánchez, Paula Ruiz‐López, Pilar González‐García, Janne Purhonen, Juan Manuel Martínez‐Gálvez, Sergio López‐Herrador, Julia Corral‐Sarasa, María Elena Díaz‐Casado, Carmen Venegas, Isaac Santos‐Pérez, Enrica Olivieri, Adriana L. Rojas, Luis Carlos López +12 morewiley +1 more sourceIntergenerational Learning in the Workplace. What About Academic Staff at Higher Education Institutions?
International Journal of Training and Development, Volume 30, Issue 1, Page 82-92, March 2026.ABSTRACT
Demographic development and hiring and retirement policies in higher education institutions (HEIs) have promoted the coexistence of different generations in university departments. Intergenerational learning (IGL) processes in the workplace are crucial for improving both individual and institutional well‐being and performance.Sheila García‐Martín, David Rodríguez‐Gómez, Diego Castro‐Ceacero, Ruth Cañón‐Rodríguez +3 morewiley +1 more sourceENVEJECIMIENTO ACTIVO:
, 2020 ABSTRACT: The paradigm of "Active Aging: A Political Framework" began to develop from the Second World Assembly on Aging in 2002. It represented a revolution and a change of thinking in today's societies, mostly, aged but healthy, with appropriate eating styles and adjusted to their needs, participating in leisure activities, with personalized exercise Victoria Pérez-de-Guzmán, José Luis Rodríguez-Díez, Ángel De-Juanas +2 moreopenaire +3 more sourcesFrailty and Health Outcomes in People 65 Years or Older Living With Dementia: A Systematic Review of the Literature
Journal of the American Geriatrics Society, Volume 74, Issue 3, Page 854-867, March 2026.ABSTRACT Introduction
Although frailty is considered a potentially modifiable risk factor for dementia, its influence on health outcomes in individuals with established dementia remains unclear. This study aims to systematize the current evidence to understand the impact of frailty on the development of adverse outcomes in older adults with dementia ...Miguel German Borda, Luis Carlos Venegas‐Sanabria, Marco Canevelli, Francesco Landi, Salomón Páez‐García, Kevin O'Hara‐Veintimilla, Lindsay Wallace, Kenneth Rockwood, Tommy Cederholm, Gustavo Duque, Mario Ulises Pérez‐Zepeda, Dag Aarsland +11 morewiley +1 more sourceAsociación entre fuerza de prensión y comorbilidades: Estudio Sabe, Ecuador, 2009
Revista Ciencias de la Salud, 2019 Introducción: el aumento de enfermedades crónicas ha motivado la creación de métodos de evaluación del adulto mayor que permitan estimar su estado general de salud. Entre estos, se ha propuesto la fuerza de prensión.Miguel Germán Borda, MD, MSc, Mario Ulises Pérez-Zepeda, MD, PhD, Camilo Gómez-Arteaga, MD, Ana María Pardo-Amaya, MD, Diego Chavarro-Carvajal, MD, MSc, Carlos Cano-Gutiérrez, MD +5 moredoaj +1 more sourceEfficacy of a Multicomponent Intervention for Frailty or Physical Function in Prefrail or Frail Older Adults: FRAILMERIT Multicenter Clinical Trial
Journal of the American Geriatrics Society, Volume 74, Issue 3, Page 658-668, March 2026.Clinical management of the older adult. ABSTRACT Objectives
Frailty is a common condition in community‐dwelling older adults with high health and socioeconomic implications. However, primary care‐led randomized trials have been scarcely tested. Design
Multicenter cluster randomized clinical trial.Adriana Abizanda Saro, Rafael García Molina, Rubén Alcantud Córcoles, Manuel Maestre Moreno, Raúl Sánchez Uceda, Ignacio Morón Merchante, Antonio Aragonés Jiménez, María Dolores González Céspedes, Pilar Montero Alía, Marta Simarro Rueda, Luis Torres Antón, Pilar Martínez García, Humberto Soriano Fernández, Marta Córcoles García, Ángel Moises Reyes Abreu, María Nuria Morcillo González, Elena García Páez, Beatriz Rodríguez Sánchez, Marta Sáez Blesa, Elisa Belén Cortés Zamora, Fernando Andrés Pretel, Almudena Avendaño Céspedes, FRAILMERIT Study Group, Aránzazu Rodríguez Ortiz, Raquel González Herreros, José Luis Carboneras Atienza, Lisbeth Rodríguez Gómez, Hugo García López, Clotilde Boix Gras, Lorena Moreno Hernández, Jesús López‐Torres Hidalgo, Maximiliano Martínez Ramírez, Francisco Escobar Rabadán, Juan Manuel Téllez Lapeira, Esther Limón Romero, Clara Soler Gimbernat, Laura Grimal Abejez, Mercé Jioménez González, Verónica Griselda Echenique Portillo, Alexandre Ortega Roca, Meritxell Carmona Cervelló, Carla Chacón Valera, Carmen Rodríguez Buza, Óscar Cobos Cano, María Julia Sánchez Maestre, Ana Fons Diaz, Javier Ibáñez Rivas, Marina Carmona García, Inmaculada Sag Lesmes, Alfredo Ortiz Arjona, Alejandro Becerra Serrano, Antonia Prieto Cuesta, Ana Sánchez Maestre, Carlos Eusebio Esparza Ferrera, Miriam Bueno León, Cristina Figueroa Martín, Noelia Díaz Hernández, Patricia Gutiérrez González, Quintina Pérez Quesada, Soraya Sotto Rodríguez, Guacimara Delgado Jiménez, María Florentina Álvarez Álvarez, Yudanis Sánchez Alpízar, Diego Aparicio Barrilero, Paloma de Teodoro Idiago, Sandra Benito Prieto, Ana Pilar Javierre Miranda, Elena Mendoza Fernández, Emma Camino Ortega, Ana de Baroja Gil deGómez, María Lafuente Yanguas, Antía Codina Rodríguez, Amelia González Gamarra, José Gutiérrez Rodríguez, José Miguel Arche Coto, Eva López Alvarez, Alvaro Revuelta Argomaniz, Cristina Alonso Bouzón, José Antonio Serra Rexach, Jennifer Mayordomo Cava, Marta Carolina Ruiz Grao, Luis Aguilar Salmerón, Alicia Noguerón García, Elena Martín Sebastiá, Elena Gómez Jiménez, Cristina Gómez Ballesteros, Pedro Abizanda +86 morewiley +1 more sourceDifferential contribution of T‐type voltage‐gated calcium channels to vascular reactivity in the aorta and renal artery of healthy rabbits
Experimental Physiology, Volume 111, Issue 3, Page 1498-1512, 1 March 2026.Abstract figure T‐type VGCCs contribute to the contraction of the rabbit aorta and modulate both contraction and vasodilation in the rabbit renal artery. α1, alpha 1 adrenergic receptor; ATR, angiotensin II receptor; Ang II, angiotensin II; CaM, calmodulin; Cav3, T‐type voltage‐gated Ca2⁺ channels; cGMP, cyclic guanidine monophosphate; EC, endothelial ...Andrea Suarez, Sol Guerra‐Ojeda, Manuel Zarzoso, Marta Serna‐García, Jose M. Vila, Eva Serna, Maria D. Mauricio +6 morewiley +1 more sourceDetecting early memory changes in preclinical Alzheimer's disease using TabCAT favorites test: Data from the European Prevention of Alzheimer's Disease (EPAD) cohort
Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.Abstract INTRODUCTION
Sensitive memory paradigms may allow the detection of subtle memory changes associated with early Alzheimer's pathology in individuals without established clinical symptomatology. METHODS
We explored the cross‐sectional association between performance on Tablet‐based Cognitive Assessment Tool (TabCAT) Favorites, a brief ...Anna Brugulat‐Serrat, Elena Tsoy, Gonzalo Sánchez‐Benavides, Marta Milà‐Alomà, Leslie S. Gaynor, Oriol Grau‐Rivera, Juan Domingo Gispert, Joel H Kramer, Katherine L Possin, for the European Prevention of Alzheimer's Disease (EPAD) Consortium +9 morewiley +1 more source