Results 41 to 50 of about 7,644 (156)

Validation of the Lubben-6 Scale to measure social support networks among older adults in Chile

MedUNAB
Introduction. Assessing social support networks requires reliable and valid instruments, which are apparently nonexistent for older adults in Chile. The objective here is to adapt and further validate the Argentine version of the Lubben-6 Social Support ...
Emilio Moyano-Diaz, Mónica Edith Jorquera-Cox, Camila Marta Oda-Montecinos, Claudia Estrada-Goic   +3 more
doaj   +1 more source

Ancianos en la investigación de medicamentos

Revista Iberoamericana de Bioética, 2020
En las últimas décadas se viene produciendo un envejecimiento de la población que es foco de atención de instituciones de ámbito mundial con objeto de promover un envejecimiento saludable.
Olga Martínez Casares, Reyes Boceta Muñoz, Marta Albert Márquez   +2 more
doaj   +1 more source

Relationship between locus coeruleus and slow‐wave sleep in aging and Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sleep disruption, particularly loss of slow‐wave sleep (SWS), is common in Alzheimer's disease (AD), but its neurobiological underpinnings remain unclear. We investigated whether locus coeruleus (LC) integrity relates to SWS across the AD continuum and whether sex and perivascular spaces (PVSs) modify these associations.
Neus Falgàs, Núria Tort‐Colet, Isabel Martín‐Sobrino, Gerard Mayà, Marta Peña‐González, Salvatore Rudilosso, Carles Gaig, Beatriz Bosch, Aurora Arqueros, Agnès Pérez‐Millan, Adrià Tort‐Merino, Guadalupe Fernández‐Villullas, Gerard Piñol‐Ripoll, Mircea Balasa, Albert Lladó, Manuel Morales Ruiz, Emma Muñoz‐Moreno, Oriol Grau‐Rivera, Alex Iranzo, Lea T. Grinberg, Raquel Sánchez‐Valle   +20 more
wiley   +1 more source

Low Frequency of Dementia with Lewy Bodies Diagnosis in a Colombian Memory Clinic

Movement Disorders Clinical Practice, Volume 13, Issue 2, Page 442-451, February 2026.
Abstract Background The global burden of dementia is increasing, particularly in low‐ and middle‐income countries. Dementia with Lewy bodies (DLB) is the second most common neurodegenerative dementia but remains underreported and frequently misdiagnosed. Its prevalence in Latin America is largely unknown.
Felipe Botero‐Rodríguez, José Manuel Santacruz‐Escudero, Miguel Germán Borda, Salomón Salazar‐Londoño, Carlos Cano‐Gutiérrez, Dag Aarsland, on behalf of COL‐DLB   +6 more
wiley   +1 more source

Evaluation of the subprograms for the Community Care of the Elderly in Mantua

Revista de Ciencias Médicas de Pinar del Río, 2019
Introduction: the evaluation of programs in Primary Health Care allows measuring the true impact of their application and arises as an instrument of accuracy and development.
Carmen Delia Cordero otero, Yuraimy Piña Moreno, Osniel Rodríguez Lemus, Alexis Izquierdo Izquierdo, Andys Regino Vega Pérez   +4 more
doaj  

A Multidomain Lifestyle Intervention Is Associated With Improved Functional Trajectories and Favorable Changes in Epigenetic Aging Markers in Frail Older Adults: A Randomized Controlled Trial

Aging Cell, Volume 25, Issue 2, February 2026.
In frail older adults, a 6‐month lifestyle intervention slowed epigenetic aging and improved functional outcomes, suggesting lifestyle strategies may delay biological aging and disability progression. ABSTRACT Frailty emerges as the intermediate stage preceding disability, but there is a gap in molecular signatures for early detection of subclinical ...
Gloria Olaso‐Gonzalez, Fernando Millan‐Domingo, Luis Garcia‐Fernandez, Elisa Garcia‐Tercero, Monica Cebrian, Cristina Garcia‐Dominguez, Juan Antonio Carbonell, German Casabo‐Valles, Jose Luis Garcia‐Gimenez, Eva Tamayo‐Torres, Juan Gambini, Francisco Jose Tarazona‐Santabalbina, Jose Vina, Maria Carmen Gomez‐Cabrera   +13 more
wiley   +1 more source

Envejecimiento normal

Revista Estomatología, 1993
El envejecimiento normal o fisiológico está más cerca de la salud que de la enfermedad; el envejecimiento como proceso natural no es deteriorante y ésta es una idea que se debe resaltar. El envejecimiento biológico comprende los cambios orgánicos estructurales y.funcionales en los seres vivos y en el ser humano a nivel macroscópico y microscópico.
openaire   +1 more source

Brain volume trajectories in Down syndrome and autosomal dominant Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION It is unknown if neurodegeneration trajectories differ between Down syndrome (DS) and autosomal dominant Alzheimer's disease (ADAD), both of which are genetic forms of Alzheimer's disease (AD). METHODS We compared brain volumes in DS, ADAD, and unaffected family members serving as controls.
James T. Kennedy, Julie K. Wisch, Anna H. Boerwinkle, Peter R. Millar, Nicole S. McKay, Adam M. Brickman, Jasmeer P. Chhatwal, Patricio Chrem Mendez, Bradley T. Christian, Anne Cohen, Carlos Cruchaga, Alisha Daniels, Shaney Flores, Benjamin L. Handen, Sigan L. Hartley, Elizabeth Head, Laura Ibanez, Sharon J. Krisnsky‐McHale, Christian la Fougere, Florence Lai, Charles M. Laymon, Joseph H. Lee, Jae‐Hong Lee, Johannes Levin, Jorge Llibre‐Guerra, David F. Aguillon, Ira T. Lott, Mark Mapstone, Eric McDade, John Morris, Sid E. O'Bryant, Julie C. Price, Michael S. Rafii, Jee Hoon Roh, H. Diana Rosas, Nicole Schupf, Charlene Supnet‐Bell, Chengjie Xiong, Shahid Zaman, Tammie L. S. Benzinger, Brian A. Gordon, Beau M. Ances, the Alzheimer's Brain Consortium – Down Syndrome, and the Dominantly Inherited Alzheimer's Network   +43 more
wiley   +1 more source

EL ENVEJECIMIENTO SOCIAL: PRESENTE Y FUTURO

Medicentro, 2016
El envejecimiento se caracteriza por cambios y transformaciones producidos por la interrelación entre factores intrínsecos (genéticos) y extrínsecos (ambientales), protectores o agresores (factores de riesgo) durante la vida. Estos cambios se manifiestan
Raidel González Rodríguez, Juan Cardentey García   +1 more
doaj  

Predicting cognitive trajectories in asymptomatic individuals at‐risk of AD: insights from a multi‐platform plasma proteomics study [PDF]

Alzheimers Dement
Abstract Background Plasma biomarkers enabling early detection of Alzheimer's disease (AD) biological hallmarks are now available. Yet, predicting cognitive decline in at‐risk individuals remains challenging due to the high variability of cognitive outcomes and lack of reliable prognostic markers.
Anastasi F, Escalante A, Segura‐Retana P, Ortiz‐Romero P, Sánchez‐Benavides G, López‐Martos D, Grau‐Rivera O, Minguillón C, del Campo M, Vilor‐Tejedor N, Suárez‐Calvet M.   +10 more
europepmc   +2 more sources