Results 51 to 60 of about 8,004 (178)
Telomeres are essential for chromosome protection and genomic stability, and telomerase function is critical for organ homeostasis. Zebrafish is a useful vertebrate model for understanding cellular and molecular mechanisms of regeneration.
Elena Martínez-Balsalobre +7 more
doaj +1 more source
Abstract INTRODUCTION We examined neurofibrillary tangle (NFT) pathology using 18F‐RO‐948 tau positron emission tomography (PET) in cognitively unimpaired individuals and its associations with amyloid plaques, fluid biomarkers, and cognition in early preclinical Alzheimer's disease (AD).
Mahnaz Shekari +32 more
wiley +1 more source
The landscape of dementia research, diagnosis, treatment, and care in Latin America
Abstract Latin America is undergoing rapid population aging alongside a rising burden of dementia. While the region holds substantial potential for dementia risk reduction, challenges remain, such as delayed diagnoses, limited access to specialized care and biomarker testing, persistent stigma, and deep‐rooted structural inequities.
Claudia K. Suemoto +41 more
wiley +1 more source
Introduction: Functional decline following hospitalization (FDH) is defined as the loss of the functional capacity to perform at least one basic activity of daily life (BADL) when being discharged from hospital; a situation compared to functional ...
Sandra Milena Castelblanco Toro +4 more
doaj +1 more source
Bases moleculares del envejecimiento. Un envejecimiento saludable
Grado en ...
openaire +1 more source
ABSTRACT Population aging is a problem that countries around the globe are facing; it comes with complex healthcare needs. Different countries take different approaches to solving these issues. In the United States, proposed legislation related to hospice and palliative care emerged from a history of hospice fraud and specialty physician shortages.
Edith‐Marie Green
wiley +1 more source
ABSTRACT Aim Mitochondrial dysfunction plays a central role in multiple neurodegenerative diseases, yet the temporal sequence of cellular events underlying neurodegeneration remains poorly defined. This study aimed to characterize the progression of neurodegeneration in a mouse model of fatal mitochondrial encephalopathy and to evaluate the therapeutic
Laura Jiménez‐Sánchez +12 more
wiley +1 more source
ABSTRACT Demographic development and hiring and retirement policies in higher education institutions (HEIs) have promoted the coexistence of different generations in university departments. Intergenerational learning (IGL) processes in the workplace are crucial for improving both individual and institutional well‐being and performance.
Sheila García‐Martín +3 more
wiley +1 more source
En tanto sujeto humano, el adulto mayor se va constituyendo en el inter-juego de factores que conforman la trama vincular y social. Es desde esta interacción social, activa y multidireccional, que el sujeto va construyendo su propio modelo de relación con el mundo.
openaire +1 more source
ABSTRACT Introduction Although frailty is considered a potentially modifiable risk factor for dementia, its influence on health outcomes in individuals with established dementia remains unclear. This study aims to systematize the current evidence to understand the impact of frailty on the development of adverse outcomes in older adults with dementia ...
Miguel German Borda +11 more
wiley +1 more source

