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Infectious Bronchitis Virus Envelope Protein Targeting: Implications for Virus Assembly
2001Coronaviruses acquire their membrane envelope by budding into the lumen of Golgi and pre-Golgi compartments. After budding, virions are thought to move in vesicles through the secretory pathway, and exit the cell when these vesicles fuse with the plasma membrane (Holmes et al., 1981, Tooze et al., 1987).
E, Corse, C E, Machamer
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Topology of hepatitis C virus envelope glycoproteins
Reviews in Medical Virology, 2003AbstractHepatitis C virus encodes two envelope glycoproteins, E1 and E2, that are released from a polyprotein precursor after cleavage by host signal peptidase(s). These proteins contain a large N‐terminal ectodomain and a C‐terminal transmembrane domain, and they assemble as a noncovalent heterodimer.
Op De Beeck, Anne, Dubuisson, J
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Glycosylation of hepatitis C virus envelope proteins
Biochimie, 2003Enveloped viruses are surrounded by a membrane derived from the host-cell that contains proteins called "envelope proteins". These proteins play a major role in virus assembly and entry. In most of the enveloped viruses, they are modified by N-linked glycosylation which is supposed to play a role in their stability, antigenicity and biological ...
Anne, Goffard, Jean, Dubuisson
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Crystalline Antigen from the Influenza Virus Envelope
Nature New Biology, 1972THE envelope of influenza viruses contains two morphologically and chemically distinct glycoproteins, a haemagglu-tinin and a neuraminidase, which recent experiments have indicated1 may be removed from the virion by treatment with the protease, bromelain.
C M, Brand, J J, Skehel
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Zika Virus Envelope Protein and Antibody Complexes
2018Zika virus (ZIKV) is a re-emerged human pathogen, belonging to a super serogroup with dengue virus. Infection of ZIKV can lead to severe congenital symptoms, such as microcephaly, in newborns and Guillain-Barré syndrome in adults. To date, no prophylactics and therapeutics are available.
Lianpan, Dai +3 more
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Quasi-enveloped hepatitis virus assembly and release
2020Hepatitis A virus (HAV) and hepatitis E virus (HEV) infections are the main causes for acute hepatitis worldwide. Both viruses had long been considered as nonenveloped viruses. However, recent work has uncovered that both viruses circulate in the bloodstream as membrane-cloaked, "quasi-enveloped" particles that are, surprisingly, infectious and likely ...
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Characterization of visna virus envelope neuraminic acid
Journal of Virology, 1977Visna virus particles inhibit influenza virus hemagglutination in an assay for neuraminic acid-containing viruses. Pretreatment of visna virus with neuraminidase abolished hemagglutination inhibition activity but did not significantly affect attachment, infectivity, or virus-induced cell fusion in sheep choroid plexus cell monolayers.
M J, August, D H, Harter, R W, Compans
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Survival of an Enveloped Virus on Toys
Pediatric Infectious Disease Journal, 2016Children's toys may carry respiratory viruses. Inactivation of a lipid-enveloped bacteriophage, Φ6, was measured on a nonporous toy at indoor temperature and relative humidity (RH). Inactivation was approximately 2log10 after 24 hours at 60% RH and 6.8log10 at 10 hours at 40% RH.
Richard L, Bearden, Lisa M, Casanova
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Human immunodeficiency virus envelope glycoproteins.
Journal of acquired immune deficiency syndromes, 1994Given the long-term clinical latency and high level of replication of human immunodeficiency virus (HIV), it is not surprising that HIV has developed a method of persistence involving production of novel variants in its proteins. Therapeutic vaccines attempt to harness enhanced immune mechanisms to control viral replication, and thus prevent disease ...
T C, Merigan, S K, Kundu
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Envelopment of the hepatitis B virus nucleocapsid
Virus Research, 2004The hepatitis B virus (HBV) is an enveloped DNA virus with an icosahedral capsid replicating via reverse transcription. The crystal structure of the capsid is known. It has a diameter of 36 nm and is formed by one protein species (C protein). The viral envelope contains three different coterminal proteins (S, M, and L proteins) spanning the membrane ...
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