Enveloped and non-enveloped virus survival on microfiber towels [PDF]
PeerJ, 2023 Background Handwashing is an important intervention which can reduce indirect disease transmission, however soap and water for handwashing purposes is not available in some low-resource regions.
Claire E. Anderson +2 more
doaj +8 more sources
Role of Lipids on Entry and Exit of Bluetongue Virus, a Complex Non-Enveloped Virus [PDF]
Viruses, 2010 Non-enveloped viruses such as members of Picornaviridae and Reoviridae are assembled in the cytoplasm and are generally released by cell lysis. However, recent evidence suggests that some non-enveloped viruses exit from infected cells without lysis ...
Bishnupriya Bhattacharya, Polly Roy
doaj +11 more sources
Size-selective downstream processing of virus particles and non-enveloped virus-like particles [PDF]
Frontiers in Bioengineering and Biotechnology, 2023 Non-enveloped virus-like particles (VLPs) are versatile protein nanoparticles with great potential for biopharmaceutical applications. However, conventional protein downstream processing (DSP) and platform processes are often not easily applicable due to
Nils Hillebrandt, Jürgen Hubbuch
doaj +8 more sources
Using cryoEM and cryoET to visualize membrane penetration of a non-enveloped virus [PDF]
STAR Protocols, 2022 Summary: Key to cell entry by non-enveloped viruses is virus-cell interactions at the cell or endosomal membrane. Here, we detail our protocols to capture such interactions between non-enveloped virus bluetongue virus (BTV) and vesicular membrane by ...
Xian Xia, Z. Hong Zhou
doaj +4 more sources
PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome. [PDF]
CellThe paraneoplastic Ma antigen (PNMA) proteins are associated with cancer-induced paraneoplastic syndromes that present with an autoimmune response and neurological symptoms. Why PNMA proteins are associated with this severe autoimmune disease is unclear.
Xu J +15 more
europepmc +8 more sources
EMC1-dependent stabilization drives membrane penetration of a partially destabilized non-enveloped virus [PDF]
eLife, 2016 Destabilization of a non-enveloped virus generates a membrane transport-competent viral particle. Here we probe polyomavirus SV40 endoplasmic reticulum (ER)-to-cytosol membrane transport, a decisive infection step where destabilization initiates this non-
Parikshit Bagchi +2 more
doaj +4 more sources
Non-enveloped virus inactivation potency of sodium dodecyl sulfate with citric and glutamic acids. [PDF]
Front MicrobiolDisinfection is one of the most important methods by which transmission of infectious diseases can be blocked, and efficacies differ depending on how they are used and the target organism. Small non-enveloped viruses are considerably less sensitive to disinfectants than enveloped viruses and vegetative bacteria or fungi and generally require strong ...
Tan YW +8 more
europepmc +5 more sources
Functional refolding of the penetration protein on a non-enveloped virus. [PDF]
Nature, 2021 A non-enveloped virus requires a membrane lesion to deliver its genome into a target cell1. For rotaviruses, membrane perforation is a principal function of the viral outer-layer protein, VP42,3. Here we describe the use of electron cryomicroscopy to determine how VP4 performs this function and show that when activated by cleavage to VP8* and VP5*, VP4
Herrmann T +7 more
europepmc +6 more sources
Multiple conformations of trimeric spikes visualized on a non-enveloped virus. [PDF]
Nat Commun, 2022 AbstractMany viruses utilize trimeric spikes to gain entry into host cells. However, without in situ structures of these trimeric spikes, a full understanding of this dynamic and essential process of viral infections is not possible. Here we present four in situ and one isolated cryoEM structures of the trimeric spike of the cytoplasmic polyhedrosis ...
Zhang Y, Cui Y, Sun J, Zhou ZH.
europepmc +7 more sources
Structural Insight into Non-Enveloped Virus Binding to Glycosaminoglycan Receptors: A Review. [PDF]
Viruses, 2021 Viruses are infectious agents that hijack the host cell machinery in order to replicate and generate progeny. Viral infection is initiated by attachment to host cell receptors, and typical viral receptors are cell-surface-borne molecules such as proteins or glycan structures.
Sorin MN, Kuhn J, Stasiak AC, Stehle T.
europepmc +7 more sources