Results 1 to 10 of about 59,053 (105)

Ritonavir Blocks Hepatitis E Virus Internalization and Clears Hepatitis E Virus In Vitro with Ribavirin [PDF]

Viruses, 2022
Hepatitis E virus (HEV) is increasingly recognized as the leading cause of acute hepatitis. Although HEV infections are mostly self-limiting, a chronic course can develop especially in those with immunocompromised state.
Putu Prathiwi Primadharsini, Shigeo Nagashima, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto   +4 more
doaj   +4 more sources

Nisoldipine Inhibits Influenza A Virus Infection by Interfering with Virus Internalization Process [PDF]

Viruses, 2022
Influenza virus infections and the continuing spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are global public health concerns. As there are limited therapeutic options available in clinical practice, the rapid development of safe,
Yingna Huang, Yinyan Li, Zhixuan Chen, Liurong Chen, Jinlong Liang, Chunyu Zhang, Zhengyin Zhang, Jie Yang   +7 more
doaj   +4 more sources

Cell surface α2,3-linked sialic acid facilitates Zika virus internalization [PDF]

Emerging Microbes and Infections, 2019
The emergence of neurotropic Zika virus (ZIKV) raised a public health emergency of global concern. ZIKV can cross the placental barrier and infect foetal brains, resulting in microcephaly, but the pathogenesis of ZIKV is poorly understood.
Chee Wah Tan, Catherine Hong Huan Hor, Swee Sen Kwek, Han Kang Tee, I-Ching Sam, Eyleen L. K. Goh, Eng Eong Ooi, Yoke Fun Chan, Lin-Fa Wang   +8 more
doaj   +4 more sources

Direct Interaction Between CD163 N-Terminal Domain and MYH9 C-Terminal Domain Contributes to Porcine Reproductive and Respiratory Syndrome Virus Internalization by Permissive Cells [PDF]

Frontiers in Microbiology, 2019
Porcine reproductive and respiratory syndrome virus (PRRSV) has a highly restricted tropism for cells of the monocyte-macrophage lineage, including porcine alveolar macrophages (PAMs).
Gaopeng Hou, Biyun Xue, Liangliang Li, Yuchen Nan, Lu Zhang, Kuokuo Li, Qin Zhao, Julian A. Hiscox, James P. Stewart, Chunyan Wu, Jingfei Wang, En-Min Zhou   +11 more
doaj   +2 more sources

Human Platelets and Influenza Virus: Internalization and Platelet Activation [PDF]

Platelets, 2022
Influenza infection has long been associated with prothrombotic outcomes in patients and platelets are the blood component predominantly responsible for thrombosis. In this review, we outline what is known about influenza interaction with human platelets,
Josiah Bote, Heather A. Corkrey, Milka Koupenova   +2 more
doaj   +2 more sources

GRP78 promotes rabies virus entry through interacting with viral receptors [PDF]

Journal of Virology
The rabies virus (RABV) is known to have four potential receptors, including the nicotinic acetylcholine receptor (nAChR), neural cell adhesion molecule (NCAM), low-affinity nerve growth factor receptor (NGFR), and metabolic glutamate receptor 2 (mGluR2).
Chong Wang, Zhiyuan Wen, Chen Wang, Qilong Liu, Hailin Zhang, Lei Shuai, Xijun Wang, Jinying Ge, Jinliang Wang, Zhigao Bu   +9 more
doaj   +2 more sources

Internalization-related host factors of common respiratory viruses [PDF]

Frontiers in Immunology
Respiratory viruses impose a substantial health burden worldwide, with viral internalization into host cells being the initial step for infection establishment.
Qiuchi Lv, Qiuchi Lv, Qiuchi Lv, Qiuchi Lv, Zhengde Xie, Zhengde Xie, Zhengde Xie, Zhengde Xie, Lili Xu, Lili Xu, Lili Xu, Lili Xu   +11 more
doaj   +2 more sources

Vesicular stomatitis virus enters cells through vesicles incompletely coated with clathrin that depend upon actin for internalization.

PLoS Pathogens, 2009
Many viruses that enter cells by clathrin-dependent endocytosis are significantly larger than the dimensions of a typical clathrin-coated vesicle.
David K Cureton, Ramiro H Massol, Saveez Saffarian, Tomas L Kirchhausen, Sean P J Whelan   +4 more
doaj   +3 more sources

Glycyrrhiza Polysaccharide Inhibits Pseudorabies Virus Infection by Interfering with Virus Attachment and Internalization

Viruses, 2022
Pseudorabies virus (PRV) is one of the most important pathogens causing serious diseases and leads to huge economic losses in the global swine industry.
Changchao Huan, Yao Xu, Wei Zhang, Bo Ni, Song Gao   +4 more
doaj   +3 more sources

Kinetic Landscape of Single Virus-like Particles Highlights the Efficacy of SARS-CoV-2 Internalization

Viruses
The efficiency of virus internalization into target cells is a major determinant of infectivity. SARS-CoV-2 internalization occurs via S-protein-mediated cell binding followed either by direct fusion with the plasma membrane or endocytosis and subsequent
Aleksandar Atemin, Aneliya Ivanova, Wiley Peppel, Rumen Stamatov, Rodrigo Gallegos, Haley Durden, Sonya Uzunova, Michael D. Vershinin, Saveez Saffarian, Stoyno S. Stoynov   +9 more
doaj   +3 more sources