Results 21 to 30 of about 59,256 (250)

Cellular Chondroitin Sulfate and the Mucin-like Domain of Viral Glycoprotein C Promote Diffusion of Herpes Simplex Virus 1 While Heparan Sulfate Restricts Mobility

Viruses, 2022
The diffusion of viruses at the cell membrane is essential to reach a suitable entry site and initiate subsequent internalization. Although many viruses take advantage of glycosaminoglycans (GAG) to bind to the cell surface, little is known about the ...
Yara Abidine, Lifeng Liu, Oskar Wallén, Edward Trybala, Sigvard Olofsson, Tomas Bergström, Marta Bally   +6 more
doaj   +1 more source

Structural studies demonstrating a bacteriophage-like replication cycle of the eukaryote-infecting Paramecium bursaria chlorella virus-1. [PDF]

PLoS Pathogens, 2017
A fundamental stage in viral infection is the internalization of viral genomes in host cells. Although extensively studied, the mechanisms and factors responsible for the genome internalization process remain poorly understood.
Elad Milrot, Eyal Shimoni, Tali Dadosh, Katya Rechav, Tamar Unger, James L Van Etten, Abraham Minsky   +6 more
doaj   +1 more source

Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner. [PDF]

PLoS Pathogens, 2010
Ebolavirus (EBOV) is an enveloped, single-stranded, negative-sense RNA virus that causes severe hemorrhagic fever with mortality rates of up to 90% in humans and nonhuman primates.
Asuka Nanbo, Masaki Imai, Shinji Watanabe, Takeshi Noda, Kei Takahashi, Gabriele Neumann, Peter Halfmann, Yoshihiro Kawaoka   +7 more
doaj   +1 more source

Internalization of rabies virus glycoprotein differs between pathogenic and attenuated virus strains

Journal of General Virology, 2023
The zoonotic rabies virus (RABV) is a non-segmented negative-sense RNA virus classified within the family Rhabdoviridae, and is the most common aetiological agent responsible for fatal rabies disease. The RABV glycoprotein (G) forms trimeric spikes that protrude from RABV virions and mediate virus attachment, entry and spread, and is a major ...
Almasoud, I., Charlton, F.W., Finke, S., Barr, J.N., Mankouri, J.   +4 more
openaire   +3 more sources

MYH9 Aggregation Induced by Direct Interaction With PRRSV GP5 Ectodomain Facilitates Viral Internalization by Permissive Cells

Frontiers in Microbiology, 2019
Prevention and control of infection by porcine reproductive and respiratory syndrome virus (PRRSV) remains a challenge, due to our limited understanding of the PRRSV invasion mechanism.
Biyun Xue, Gaopeng Hou, Guixi Zhang, Jingjing Huang, Liangliang Li, Yuchen Nan, Yang Mu, Lizhen Wang, Lu Zhang, Ximeng Han, Xiaolei Ren, Qin Zhao, Chunyan Wu, Jingfei Wang, En-Min Zhou   +14 more
doaj   +1 more source

Effect of human cytomegalovirus (HCMV) US27 on CXCR4 receptor internalization measured by fluorogen-activating protein (FAP) biosensors. [PDF]

PLoS ONE, 2017
Human cytomegalovirus (HCMV) is a widespread pathogen and a member of the Herpesviridae family. HCMV has a large genome that encodes many genes that are non-essential for virus replication but instead play roles in manipulation of the host immune ...
Jordan M Boeck, Juliet V Spencer
doaj   +1 more source

Heat Shock Protein Member 8 (HSPA8) Is Involved in Porcine Reproductive and Respiratory Syndrome Virus Attachment and Internalization

Microbiology Spectrum, 2022
Porcine reproductive and respiratory syndrome virus (PRRSV), a porcine arterivirus, causes severe financial losses to global swine industry. Despite much research, the molecular mechanisms of PRRSV infection remains to be fully elucidated. In the current
Lei Wang, Rui Li, Rui Geng, Longxiang Zhang, Xin-xin Chen, Songlin Qiao, Gaiping Zhang   +6 more
doaj   +1 more source

Changes to virus taxonomy and the International Code of Virus Classification and Nomenclature ratified by the International Committee on Taxonomy of Viruses (2019) [PDF]

Archives of Virology, 2019
This article reports the changes to virus taxonomy approved and ratified by the International Committee on Taxonomy of Viruses (ICTV) in February 2019. Of note, in addition to seven new virus families, the ICTV has approved, by an absolute majority, the creation of the realm Riboviria, a likely monophyletic group encompassing all viruses with positive ...
Peter J. Walker, Stuart G. Siddell, Elliot J. Lefkowitz, Arcady R. Mushegian, Donald M. Dempsey, Bas E. Dutilh, Balázs Harrach, Robert L. Harrison, R. Curtis Hendrickson, Sandra Junglen, Nick J. Knowles, Andrew M. Kropinski, Mart Krupovic, Jens H. Kuhn, Max Nibert, Luisa Rubino, Sead Sabanadzovic, Peter Simmonds, Arvind Varsani, Francisco Murilo Zerbini, Andrew J. Davison   +20 more
openaire   +9 more sources

Hepatitis B Virus Entry into Cells

Cells, 2020
Hepatitis B virus (HBV), an enveloped partially double-stranded DNA virus, is a widespread human pathogen responsible for more than 250 million chronic infections worldwide.
Charline Herrscher, Philippe Roingeard, Emmanuelle Blanchard   +2 more
doaj   +1 more source

Curcumin is a promising inhibitor of genotype 2 porcine reproductive and respiratory syndrome virus infection

BMC Veterinary Research, 2017
Background Porcine reproductive and respiratory syndrome virus (PRRSV) could lead to pandemic diseases and huge financial losses to the swine industry worldwide.
Taofeng Du, Yunpeng Shi, Shuqi Xiao, Na Li, Qin Zhao, Angke Zhang, Yuchen Nan, Yang Mu, Yani Sun, Chunyan Wu, Hongtao Zhang, En-Min Zhou   +11 more
doaj   +1 more source