Results 11 to 20 of about 157,420 (243)

Escape of non-enveloped virus from intact cells. [PDF]

Virology, 2015
How do viruses spread from cell to cell? Enveloped viruses acquire their surrounding membranes by budding. If a newly enveloped virus has budded through the plasma membrane, it finds itself outside the cell immediately. If it has budded through the bounding membrane of an internal compartment such as the ER, the virus finds itself in the lumen, from ...
Bird SW, Kirkegaard K.
europepmc   +5 more sources

Axon myelin transfer of a non-enveloped virus. [PDF]

PLoS ONE, 2007
We showed previously that Theiler's virus, a neurotropic non-enveloped picornavirus of mouse, traffics from the axon of infected neurons into the surrounding myelin. When this traffic is interrupted, as in the shiverer mouse which bears a mutation in the
Jean-Pierre Roussarie, Claude Ruffié, Julia M Edgar, Ian Griffiths, Michel Brahic   +4 more
doaj   +4 more sources

Non-enveloped virus membrane penetration: New advances leading to new insights. [PDF]

PLoS Pathog, 2022
Host cell membranes pose a particular challenge for non-enveloped viruses. Whereas enveloped viruses enter cells by fusing their lipid envelopes with the cellular membrane, non-enveloped viruses generally must (1) enter cells via endocytosis, then (2) penetrate the cellular endomembrane to reach the cytosol. Only then can the viruses begin to replicate
Pletan ML, Tsai B.
europepmc   +7 more sources

Cellular phosphoinositides and the maturation of bluetongue virus, a non-enveloped capsid virus [PDF]

Virology Journal, 2013
Bluetongue virus (BTV), a member of Orbivirus genus in the Reoviridae family is a double capsid virus enclosing a genome of 10 double-stranded RNA segments. A non-structural protein of BTV, NS3, which is associated with cellular membranes and interacts with outer capsid proteins, has been shown to be involved in virus morphogenesis in infected cells ...
Bhattacharya, Bishnupriya, Roy, Polly
openaire   +6 more sources

Inactivation of non-enveloped virus by 1,5 iodonaphthyl azide. [PDF]

BMC Res Notes, 2015
A photoactive hydrophobic agent 1,5-iodonaphthyl-azide (INA), has been previously shown to completely inactivate the enveloped viruses. INA sequesters into the lipid bilayer of the virus envelope and upon UV-irradiation bind to the hydrophobic domains of the envelope glycoproteins.
Gupta P, Sharma A, Mathias V, Raviv Y, Blumenthal R, Maheshwari RK.   +5 more
europepmc   +4 more sources

Egress-enhancing mutation reveals the inefficiency of non-enveloped virus cell exit. [PDF]

PLoS Biol
Viruses encounter a range of selective pressures, but inefficiencies during replication can be masked. To uncover factors that limit viral replication, we used forward genetics to enrich for a murine norovirus (MNV) mutant with faster replication.
Rodriguez-Irizarry VJ, Maples RW, Pfeiffer JK.   +2 more
europepmc   +5 more sources

Complexity and ultrastructure of infectious extracellular vesicles from cells infected by non-enveloped virus. [PDF]

Sci Rep, 2020
Abstract Enteroviruses support cell-to-cell viral transmission prior to their canonical lytic spread of virus. Poliovirus (PV), a prototype for human pathogenic positive-sense RNA enteroviruses, and picornaviruses in general, transport multiple virions en bloc via infectious
Yang JE, Rossignol ED, Chang D, Zaia J, Forrester I, Raja K, Winbigler H, Nicastro D, Jackson WT, Bullitt E.   +9 more
europepmc   +4 more sources

PNMA2 forms non-enveloped virus-like capsids that trigger paraneoplastic neurological syndrome

, 2023
Abstract The paraneoplastic Ma antigen ( PNMA ) genes are associated with cancer-induced paraneoplastic syndromes that present with neurological symptoms and autoantibody production. How PNMA proteins trigger a severe autoimmune disease is unclear.
Xu J, Erlendsson S, Singh M, Regier M, Ibiricu I, Day GS, Piquet AL, Clardy SL, Feschotte C, Briggs JAG, Shepherd JD.   +10 more
europepmc   +3 more sources

Integrin α3 is involved in non-enveloped hepatitis E virus infection

Virology, 2019
Hepatitis E virus (HEV) causes acute and fulminant hepatitis worldwide. Although enveloped (e) and non-enveloped (ne) forms of HEV have been discovered, host factors involved in infection, including receptors, remain to be elucidated. Here, we identified integrin α3 (encoded by ITGA3), a protein that binds and responds to the extracellular matrix, as ...
Masayuki Saijo, Hiroyuki Shimizu, Ryuichi Sugiyama   +2 more
exaly   +3 more sources

Exploring Hydroxytyrosol as a Promising Virucidal Agent: In Silico and In Vitro Insights into Enveloped Viruses [PDF]

Current Issues in Molecular Biology
The research investigates synthetic hydroxytyrosol (HT) antiviral properties against enveloped and non-enveloped viruses using in silico and in vitro methods.
Hanan El Ouadi, Zineb Rhazzar, Barbara Poddesu, Boutaina Addoum, Laila Benbacer, Franco Lori, Siham Fellahi, Davide De Forni, Omar Nyabi, Jean-Luc Gala, Elmostafa El Fahime, Saber Boutayeb, Lahcen Belyamani, Khalid Ennibi, Ouafaa Fassi Fehri, Nadia Touil   +15 more
doaj   +2 more sources