Results 41 to 50 of about 75,685 (267)

Orthobunyavirus ultrastructure and the curious tripodal glycoprotein spike [PDF]

open access: yes, 2013
The genus <i>Orthobunyavirus</i> within the family <i>Bunyaviridae</i> constitutes an expanding group of emerging viruses, which threaten human and animal health.
McLees, A.   +42 more
core   +1 more source

Induction of Hepatitis E Virus Anti-ORF3 Antibodies from Systemic Administration of a Muscle-Specific Adeno-Associated Virus (AAV) Vector

open access: yesViruses, 2022
The hepatitis E virus (HEV) is a major global health problem, leading to large outbreaks in the developing world and chronic infections in the developed world. HEV is a non-enveloped virus, which circulates in the blood in a quasi-enveloped form.
Lars Maurer   +6 more
doaj   +1 more source

In vitro permissivity of bovine cells for wild-type and vaccinal myxoma virus strains [PDF]

open access: yes, 2007
Myxoma virus (MYXV), a leporide-specific poxvirus, represents an attractive candidate for the generation of safe, non-replicative vaccine vector for non-host species.
Jean-Luc Duteyrat   +18 more
core   +1 more source

Identification of novel neutralizing determinants for protection against HCV

open access: yesHepatology, EarlyView., 2022
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua   +12 more
wiley   +1 more source

Nucleocapsid and glycoprotein organization in an enveloped virus

open access: yesCell, 1995
Alphaviruses are a group of icosahedral, positive-strand RNA, enveloped viruses. The membrane bilayer, which surrounds the approximately 400 A diameter nucleocapsid, is penetrated by 80 spikes arranged in a T = 4 lattice. Each spike is a trimer of heterodimers consisting of glycoproteins E1 and E2.
Cheng, RH   +6 more
openaire   +4 more sources

Functional reconstitution of influenza virus envelopes. [PDF]

open access: yesThe EMBO Journal, 1987
We have examined several procedures for the reconstitution of influenza virus envelopes, based on detergent removal from solubilized viral membranes. With octylglucoside, no functionally active virosomes are formed, irrespective of the rate of detergent removal: in the final preparation the viral spike proteins appear predominantly as rosettes. Protein
STEGMANN, T   +5 more
openaire   +3 more sources

Structures of enveloped virions determined by cryogenic electron microscopy and tomography : Advances in Virus Research [PDF]

open access: yes, 2019
Enveloped viruses enclose their genomes inside a lipid bilayer which is decorated by membrane proteins that mediate virus entry. These viruses display a wide range of sizes, morphologies and symmetries.
Kim, Young Chan   +7 more
core   +1 more source

Enhancement of Enveloped Virus Entry by Phosphatidylserine [PDF]

open access: yesJournal of Virology, 2005
ABSTRACT Enveloped virus vectors are used in a wide variety of applications. We have discovered that treatment of cultured cells with phosphatidylserine (PS) liposomes can increase virus vector infection by up to 20-fold. This effect does not abrogate virus receptor requirements, is specific to PS compared to other phospholipids, and is ...
David A, Coil, A Dusty, Miller
openaire   +2 more sources

Characterization of a quasi-enveloped, fast replicating hepevirus from fish and its use as hepatitis E virus surrogate [PDF]

open access: yes, 2019
Hepatitis E virus (HEV) is an emerging concern for the safety of plasma-derived medicinal products. The lack of an efficient cell culture system hampers the studies on HEV biology as well as validation studies to test the capacity of virus reduction ...
Roth, Nathan J.   +3 more
core   +1 more source

Evaluation of the effectiveness of the SurePure Turbulator ultraviolet-C irradiation equipment on inactivation of different enveloped and non-enveloped viruses inoculated in commercially collected liquid animal plasma.

open access: yesPLoS ONE, 2019
The objective of this study was to evaluate the effectiveness of the SurePure Turbulator ultraviolet-C (UV-C, 254 nm wavelength) irradiation equipment on inactivation of different enveloped and non-enveloped viruses in commercially collected liquid ...
Elena Blázquez   +10 more
doaj   +1 more source

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