Results 41 to 50 of about 75,685 (267)
Orthobunyavirus ultrastructure and the curious tripodal glycoprotein spike [PDF]
The genus <i>Orthobunyavirus</i> within the family <i>Bunyaviridae</i> constitutes an expanding group of emerging viruses, which threaten human and animal health.
McLees, A. +42 more
core +1 more source
The hepatitis E virus (HEV) is a major global health problem, leading to large outbreaks in the developing world and chronic infections in the developed world. HEV is a non-enveloped virus, which circulates in the blood in a quasi-enveloped form.
Lars Maurer +6 more
doaj +1 more source
In vitro permissivity of bovine cells for wild-type and vaccinal myxoma virus strains [PDF]
Myxoma virus (MYXV), a leporide-specific poxvirus, represents an attractive candidate for the generation of safe, non-replicative vaccine vector for non-host species.
Jean-Luc Duteyrat +18 more
core +1 more source
Identification of novel neutralizing determinants for protection against HCV
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua +12 more
wiley +1 more source
Nucleocapsid and glycoprotein organization in an enveloped virus
Alphaviruses are a group of icosahedral, positive-strand RNA, enveloped viruses. The membrane bilayer, which surrounds the approximately 400 A diameter nucleocapsid, is penetrated by 80 spikes arranged in a T = 4 lattice. Each spike is a trimer of heterodimers consisting of glycoproteins E1 and E2.
Cheng, RH +6 more
openaire +4 more sources
Functional reconstitution of influenza virus envelopes. [PDF]
We have examined several procedures for the reconstitution of influenza virus envelopes, based on detergent removal from solubilized viral membranes. With octylglucoside, no functionally active virosomes are formed, irrespective of the rate of detergent removal: in the final preparation the viral spike proteins appear predominantly as rosettes. Protein
STEGMANN, T +5 more
openaire +3 more sources
Structures of enveloped virions determined by cryogenic electron microscopy and tomography : Advances in Virus Research [PDF]
Enveloped viruses enclose their genomes inside a lipid bilayer which is decorated by membrane proteins that mediate virus entry. These viruses display a wide range of sizes, morphologies and symmetries.
Kim, Young Chan +7 more
core +1 more source
Enhancement of Enveloped Virus Entry by Phosphatidylserine [PDF]
ABSTRACT Enveloped virus vectors are used in a wide variety of applications. We have discovered that treatment of cultured cells with phosphatidylserine (PS) liposomes can increase virus vector infection by up to 20-fold. This effect does not abrogate virus receptor requirements, is specific to PS compared to other phospholipids, and is ...
David A, Coil, A Dusty, Miller
openaire +2 more sources
Characterization of a quasi-enveloped, fast replicating hepevirus from fish and its use as hepatitis E virus surrogate [PDF]
Hepatitis E virus (HEV) is an emerging concern for the safety of plasma-derived medicinal products. The lack of an efficient cell culture system hampers the studies on HEV biology as well as validation studies to test the capacity of virus reduction ...
Roth, Nathan J. +3 more
core +1 more source
The objective of this study was to evaluate the effectiveness of the SurePure Turbulator ultraviolet-C (UV-C, 254 nm wavelength) irradiation equipment on inactivation of different enveloped and non-enveloped viruses in commercially collected liquid ...
Elena Blázquez +10 more
doaj +1 more source

