Results 131 to 140 of about 21,199,011 (380)
Imagining 'environment' in sustainable development [PDF]
The paper presents an argument for a broader and more complex definition of environment than that currently offered in sustainable development discourse and practice.
Farrelly, Trisia Angela
core
Indiscriminate Separation, under the Same Environment, a Cause of Divergence [PDF]
John T. Gulick
openalex +1 more source
Heavy metal pollution in the environment and their toxicological effects on humans
J. Briffa, E. Sinagra, R. Blundell
semanticscholar +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura+8 more
wiley +1 more source
Book review: Environment and Empire [PDF]
This article reviews the book: “Environment and Empire”, by William Beinart and Lotte Hughes, Oxford University Press ...
Beattie, James John
core +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri+5 more
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
VARIATION OF IRRADIATION EFFECTS ON MICROORGANISMS IN RELATION TO PHYSICAL CHANGES OF THEIR ENVIRONMENT [PDF]
W.S. Moos
openalex +1 more source
Erratum to: Genes and Environment, Vol. 39
Genes and Environment
doaj +1 more source
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source