Results 151 to 160 of about 21,998,893 (378)

Worldwide trends in tracing poly- and perfluoroalkyl substances (PFAS) in the environment

, 2019
Shoji F. Nakayama, Mitsuha Yoshikane, Yu Onoda, Yukiko Nishihama, Miyuki Iwai‐Shimada, M. Takagi, Yayoi Kobayashi, Tomohiko Isobe   +7 more
openalex   +1 more source

Environment Programme, United Nations Framework Convention on Climate Change and the World Health Organization [PDF]

have pledged to: 1. Eradicate extreme poverty and hunger 2. Achieve universal primary education 3. Promote gender equality and empower women 4. Reduce child mortality 5. Improve maternal health 6. Combat HIV/AIDS, malaria and other diseases 7.

core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Fostering Learner Autonomy in English for Science: A Collaborative Digital Video Project in a Technological Learning Environment

, 2011
Christoph A. Hafner, Lindsay Miller
openalex   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

AN ECONOMETRIC PERSPECTIVE ON PUBLIC ENVIRONMENTAL CAPITAL FORMATION AND INDUSTRIAL EMISSIONS: EVIDENCE FROM SEVEN EU COUNTRIES [PDF]

Global Economic Observer
This paper investigates the dynamics and relationship between greenhouse gas emissions from industrial processes and product use (GHG), and general government expenditures on environmental protection in gross fixed capital formation (GFCF).
GEORGE-CORNEL DUMITRESCU
doaj  

MALARIA VECTOR PRODUCTIVITY IN RELATION TO THE HIGHLAND ENVIRONMENT IN KENYA [PDF]

, 2006
Noboru Minakawa, Elizabeth Omukunda, Guofa Zhou, Andrew K. Githeko, Guiyun Yan   +4 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Morphometric characteristics of Lake Limboto as critical lake in Gorontalo Province, Indonesia

Jurnal Natural
This research aims to investigate the factors leading to siltation in Lake Limboto by analyzing its morphometric characteristics gathered through direct field measurements and remote sensing using Geographic Information System (GIS).
RAGHEL YUNGINGER, INDRIATI MARTHA PATUTI, IDAWATI SUPU, NURFITRI ABDUL GAFUR, MUHAMMAD ZULKIFLI, ELFIRAWATI HASAN, ZAKIA MASRURAH, SITI ZULAIKAH, TISEN TISEN   +8 more
doaj   +1 more source