Results 51 to 60 of about 15,073,133 (303)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Graph-RAT programming environment [PDF]

, 2009
Graph-RAT is a new programming environment specializing in relational data mining. It incorporates a number of different techniques into a single framework for data collection, data cleaning, propositionalization, and analysis. The language is functional
McEnnis, Daniel
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Associations of heart rates and respiratory rates with lifestyle and environmental factors in toddlers: a nationwide cohort study

BMC Pediatrics
Background Heart rate (HR) and respiratory rate (RR) are key vital signs, yet few large studies have reported their normal values in toddlers. We thus assessed HR and RR in two-year-old Japanese children.
Keita Kanamori, Tomohisa Suzuki, Chiharu Ota, The Japan Environment Children’s Study Group   +3 more
doaj   +1 more source

Environment, innovation and productivity: application of a CDM model to the spanish service sector [PDF]

, 2016
The main aim of this study is to determine the impact of innovation on productivity in service sector companies — especially those in the hospitality sector — that value the reduction of environmental impact as relevant to the innovation process. We used
Campos-Soria, Juan Antonio, García-Pozo, Alejandro, Marchante-Mera, Andrés Jesús   +2 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Environmental enrichment, age and PPARα interact to regulate proliferation in neurogenic niches

Frontiers in Neuroscience, 2016
Peroxisome proliferator-activated receptor alpha (PPARα) ligands have been shown to modulate recovery after brain insults such as ischemia and irradiation by enhancing neurogenesis. In the present study, we investigated the effect of the genetic deletion
Margarita ePerez-Martin, Patricia eRivera, Eduardo eBlanco, Clara eLorefice, Juan eDecara, FRANCISCO JAVIER ePAVON, Antonia eSerrano, FERNANDO eRODRIGUEZ DE FONSECA, JUAN eSUAREZ   +8 more
doaj   +1 more source

Random environment on coloured trees

, 2007
In this paper, we study a regular rooted coloured tree with random labels assigned to its edges, where the distribution of the label assigned to an edge depends on the colours of its endpoints.
Menshikov, Mikhail, Petritis, Dimitri, Volkov, Stanislav   +2 more
core   +4 more sources

Implementation of a Hybrid Teaching Environment for a Traffic Engineering Course [PDF]

, 2019
Students learn in different styles. They learn via hearing and visualizing. They can also reflect and act upon what is presented to them. Afterwards, they start to reason in a logical and intuitive ways as well as memorizing and visualizing, and ...
Souliman, Mena
core   +1 more source