Results 61 to 70 of about 9,656,167 (251)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
, 2008 No known reports between 2003 and 2007 2008 onward published biennially "The publication of the 2008 Kansas Environment report represents the return to a biennial report for the Division of Environment at the Kansas Department of Health and Environment."
Kansas. Department of Health and Environment
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Mенаџмент у хотелијерству и туризму, 2013 Degradation of enviroment represents a global problem, and its moving with an unpresidented pace. Due to human activities, during second half of the twentieth century, Earths ecosystem suffered transformation faster than any period in the worlds history.
Snežana Knežević +2 more
doaj
ECOLABELS FOR LEATHER AND LEATHER PRODUCTS [PDF]
Annals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2017 Nowadays, there is an increasing demand for consumer goods ecolabelling, coming from consumers concern for adverse environmental impacts of industrial pollution and manufacturers need to protect their existing markets and to expand into new ones ...
BUCIŞCANU Ingrid - Ioana
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Global environment outlook GEO-4: Environment for development [PDF]
The Global Environment Outlook: environment for development (GEO-4) report is published in what may prove to be a remarkable year – a year when humanity faced up to the scale and pace of environmental degradation with a new sense of realism and honesty ...
United Nations Environment Programme
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source