Results 121 to 130 of about 3,674,725 (306)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Retracted: A Model for Evaluating the Effectiveness of Precise Governance of Social Assistance from a Management Perspective and Environment of Public Health. [PDF]

J Environ Public Health, 2023
Environmental And Public Health JO.
europepmc   +1 more source

Gradients of the Intergenerational Transmission of Health in Developing Countries [PDF]

This paper investigates the sensitivity of the intergenerational transmission of health to exogenous changes in income, education and public health, changes that are often delivered by economic growth.
Bhalotra, Sonia R., Rawlings, Samantha
core  

Barren Lands and Barren Bodies In Navajo Nation: Indian Women WARN about Uranium, Genetics, and Sterilization [PDF]

, 2019
Founded by Native American women in 1974, Women of All Red Nations (WARN) insisted that the ongoing Indian public health crisis could not be properly understood exclusively within the context of the exploitation and pollution of the physical environment.
Bolton, Marie, Unger, Nancy C.
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

E-waste scenario in South-Asia: an emerging risk to environment and public health. [PDF]

Environ Anal Health Toxicol, 2022
Priyashantha AKH, Pratheesh N, Pretheeba P.   +2 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Biodistribution of cerium dioxide and titanium dioxide nanomaterials in rats after single and repeated inhalation exposures

Particle and Fibre Toxicology
Background Physiologically based kinetic models facilitate the safety assessment of inhaled engineered nanomaterials (ENMs). To develop these models, high quality datasets on well-characterized ENMs are needed. However, there are at present, several data
Ilse Gosens, Jordi Minnema, A. John F. Boere, Evert Duistermaat, Paul Fokkens, Janja Vidmar, Katrin Löschner, Bas Bokkers, Anna L. Costa, Ruud J.B. Peters, Christiaan Delmaar, Flemming R. Cassee   +11 more
doaj   +1 more source

The Impact of Sustainable Growth and Sustainable Environment on Public Health: A Study of GCC Countries. [PDF]

Front Public Health, 2022
Khan MN, Aziz G, Khan MS.
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source