Results 121 to 130 of about 25,414,586 (332)

Approximated models for aerodynamic coefficients estimation in a multidisciplinary design environment [PDF]

, 2011
In this paper variable fidelity analyses are investigated. Moreover different kind of approximations to be used in a wide multidisciplinary design environment for aircraft design are built.
Maggiore, Paolo, Mainini, Laura, Tosetti, Marco   +2 more
core  

Material Metabolism: Reducing Risk through Flexible Formwork Substitution

Buildings
For this special issue, sustainability and safety are discussed through the tropes of both material and work process substitution. As an architecture and industrial design team, we examine the potential of William McDonough’s and Michael Braungart’s ...
Mike Louw, Sally Farrah, Max Maxwell, Sam Tomkins   +3 more
doaj   +1 more source

Reaction Environment Design for Multigram Synthesis via Sonogashira Coupling over Heterogeneous Palladium Single-Atom Catalysts. [PDF]

ACS Sustain Chem Eng, 2023
Poier D, Akl DF, Lucas E, Machado AR, Giannakakis G, Mitchell S, Guillén-Gosálbez G, Marti R, Pérez-Ramírez J.   +8 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Design and analysis considerations for deployment mechanisms in a space environment [PDF]

, 1982
On the second flight of the INTELSAT V spacecraft the time required for successful deployment of the north solar array was longer than originally predicted. The south solar array deployed as predicted.
Gore, J. V., Plescia, C. T., Vorlicek, P. L.   +2 more
core   +1 more source

Retracted: Analysis on the Characteristics and Influence of the Teaching Environment Design of College Politics Course under the Campus Humanistic Governance Environment. [PDF]

J Environ Public Health, 2023
Environmental And Public Health JO.
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Application of machine learning-based AI in defect monitoring of earth retaining structures and tunnels of transport systems: A review

Transportation Engineering
The transport system in a modern city is a complex and challenging web of roads, railways, metros, and pedestrian networks. The networks consist of various components, including transport tunnels and earth-retaining structures (ERS).
Md Zahidul Islam, Chin Jian Leo, Ju Jia Zou, Eileen An, Samanthika Liyanapathirana, Pan Hu, Bo Xiao, Stanley Yuen   +7 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Building a Common Ground – The Use of Design Representation Cards for Enhancing Collaboration between Industrial Designers and Engineering Designers [PDF]

, 2009
To achieve success in today’s commercial environment, manufacturers have progressively adopted collaboration strategies. Industrial design has been increasingly used with engineering design to enhance competitiveness.
Campbell, Ian, Evans, Mark A, Pei, Eujin
core