Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The possibilities of utilizing natural zeolites in the environmental protection [PDF]
Acta Montanistica Slovaca, 1999 The natural zeolites have been know as the material of a wide spectrum of aplicability in different branches of national economy. As naturally occuring alumosilicate minerals of specific crystal structure they possess significant properties. In the paper
Leščinská Marcela +2 more
doaj
Analysis of the Key Factors of Ecological Environment Protection in the National Economic Sustainable Development Goals. [PDF]
J Environ Public Health, 2022 Long H.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Análisis a la eficiencia de las fuentes de energía renovable
Ingenierías USBMed, 2010 A pesar de tener el apoyo del público y numerosas ventajas sobre otras fuentes de energía, a las tecnologías renovables se les ha caracterizado repetidamente de no poder satisfacer nuestras necesidades energéticas, y se han presentado sólo como una ...
Jennifer Wangong , Penelope Daniel
doaj
Analysis on Logistics Efficiency Measurement of New Western Land-Sea Corridor under the Background of "Double Carbon" and Ecological Environment Protection. [PDF]
J Environ Public Health, 2023 Zhou T, Li W.
europepmc +1 more source
Selection of Marine Conservation Zones
, 2013 Marine Conservation Zones may contribute to the protection and recovery of the marine environment. This POSTnote examines the process and approach used to select and designate zones, and difficulties in identifying and managing suitable ...
Brown, Alastair, Wentworth, Jonathan
core
A proof of concept on real-time air quality monitoring system [PDF]
, 2017 According to the Department of Environment Malaysia, Air Pollutant Index (API) is an indicator for the air quality status at any particular area. API is calculated based on average concentration of air pollutants such as Sulphur Dioxide (SO2), Nitrogen ...
Ibrahim, Noraini +2 more
core
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
Molecular Oncology, EarlyView.PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source