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Selection of Marine Conservation Zones
, 2013 Marine Conservation Zones may contribute to the protection and recovery of the marine environment. This POSTnote examines the process and approach used to select and designate zones, and difficulties in identifying and managing suitable ...
Brown, Alastair, Wentworth, Jonathan
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Investor Protection and Equity Markets [PDF]
We present a simple model of an entrepreneur going public in an environment with poor legal protection of outside shareholders. The model incorporates elements of Becker's (1968) crime and punishment' framework into a corporate finance environment of ...
Andrei Shleifer, Daniel Wolfenson
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Property, construction process and environment. Three elements of legal structure which regulate our right to housing : a strange causal link [PDF]
, 2015 32 páginas.Trabajo de Curso de Experto Universitario en Derecho Español Impartido en Inglés: Estudio de Conjunto (2014/15). The fundamental object of analysis of the Project presented here is the relationship between Property and Environment, and the ...
Sierra Quero, Francisco José
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FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Tourism Development Perspectives in the Putna – Vrancea Nature Park [PDF]
During the last years tourism in natural environments noted an increase in demand from the part of touristy products consumers. The Vrancea mountain area, though having a divers touristy potential, is not very well known on the tourism market. The Putna –
Gina Craescu
core
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source