Results 151 to 160 of about 10,893,724 (294)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Change in an urban food environment within a single year: Considerations for food-environment research and community health. [PDF]

Prev Med Rep, 2020
Lucan SC, Maroko AR, Jin A, Chen A, Pan C, Sosa G, Schechter CB.   +6 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Nanomaterials in the Environment: Research Hotspots and Trends. [PDF]

Int J Environ Res Public Health, 2019
Li C, Huang G, Cheng G, Zheng M, Zhou N.
europepmc   +1 more source

UALTC 2010 The Graduate Virtual Research Environment: Networked Learning Across Departmental Boundaries [PDF]

submitted to the Annual Learning and Teaching Conference 2010.

core  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Fifteen Years of Health-and-Environment Research in Slovenia. [PDF]

Zdr Varst
Carli T, Kukec A, Zaletel-Kragelj L, Eržen I.   +3 more
europepmc   +1 more source

The research environment of Universities [PDF]

Tertiary Education and Management, 1998
Javier Vidal, Miguel Quintanilla
openaire   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

A systematic scoping review of urban food environment research, interventions, and measurement approaches in eight low- and middle-income countries. [PDF]

Int J Behav Nutr Phys Act
Margolies A, Amunga D, Choo EM.
europepmc   +1 more source