Results 161 to 170 of about 10,893,724 (294)

[Research in an Extreme Environment : Research Practices of Underwater Archaeology at Cape Gelidonya (1958-1961)]. [PDF]

NTM, 2021
Heine EC.
europepmc   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Digital platform-based conceptual framework for food environment research in China. [PDF]

Public Health Nutr
Cong N, Koh K, Kwan MP, Zhang H.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Research into Environment [PDF]

Nature, 1967
openaire   +2 more sources

Scaling up natural experimental studies: harnessing emerging technologies to transform physical activity and built environment research. [PDF]

Int J Behav Nutr Phys Act
Benton JS, Wende ME, Ryan DJ, Thompson RL, Hipp JA.   +4 more
europepmc   +1 more source

IMARINE - Virtual Research Environments Activity Report

, 2012
Virtual Research Environments are among the main products the iMarine project is requested to deliver in order to serve the needs of the Ecosystem Approach Community of Practice. The deployment and operation of a Virtual Research Environment is a task involving the exploitation of technologies that have been developed as well as the development of new ...
Ellenbroek A., Candela L., Pagano P.
openaire   +3 more sources

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Design of Three-Dimensional Magnetic Probe System for Space Plasma Environment Research Facility (SPERF). [PDF]

Sensors (Basel)
Yang J, Xie J, Ling W, Guan J, Huang K, Chen F, Peng G, Tang H, Zhou H, E P.   +9 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source