Results 71 to 80 of about 10,893,724 (294)
QUALITY IN TERMS OF COST EFFICIENCY [PDF]
Revista Română de Statistică, 2010 The studies based on using selective research are one of the maininstruments in the strategy building process at the managing level of academic facilities and collecting the data in the most effective way possible is one of the main problems that this ...
Vasile Alecsandru STRAT
doaj
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A Bibliometric Analysis of the Outdoor Thermal Environment Based on CiteSpace
BuildingsThe outdoor thermal environment (OTE) is closely related to sustainable urban development and human living, and related research has attracted widespread attention.
Chao Xie, Tangjun Feng, Li Hu
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Research Environment After COVID-19
Journal of Eta Maritime Science, 2021 Selçuk Nas
doaj +1 more source
Accounting and Environment: An Analysis of Academic Literature in Journals
Revista Sociedade, Contabilidade e Gestão, 2014 Since ancient times economic activity has brought environmental impacts. However, in recent years the society has been showing an increasing concern with environmental issues.
José Ricardo Maia de Siqueira
doaj
CSRE: a speech research environment
2nd International Conference on Spoken Language Processing (ICSLP 1992), 1992 CSRE (The Canadian Speech Research Environment) is a comprehensive, microcomputer-based system designed to support speech research using IBM/AT-compatible micro-computers. CSRE provides a powerful, low-cost facility in support of speech research, using mass-produced and widely available hardware.
Donald G. Jamieson +3 more
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source