Results 81 to 90 of about 10,893,724 (294)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Measuring the Global Research Environment: Information Science Challenges for the 21st Century [PDF]
“What does the global research environment look like?” This paper presents a summary look at the results of efforts to address this question using available indicators on global research production.
Anderson, Caryn, Bammer, Gabriele
core
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
TextGrid – Virtual Research Environment for the Humanities
The TextGrid research group, a consortium of 10 research institutions in Germany, is developing a virtual research environment for researchers in the arts and humanities that provides services and tools for the analysis of text data and supports the ...
Heike Neuroth +2 more
doaj +3 more sources
Research perspectives in the domain of the built environment
Riccardo Gulli
doaj +1 more source
2490 Research navigation services and onboarding: Succeeding in the research environment
OBJECTIVES/SPECIFIC AIMS: Describe (1) the components of the research navigation service and consultation/onboarding program, (2) use and adoption of the services, and (3) the overall satisfaction from the research community.
Rebecca Namenek Brouwer, Geeta Swamy
doaj +1 more source
GATT AND THE ENVIRONMENT: POLICY RESEARCH NEEDS [PDF]
This paper is a brief review of current problems in which trade and environmental issues intersect. After a statement of these problems, it focuses on some recent empirical research and future research needs of special relevance to agricultural ...
Harold, Courtney, Runge, C. Ford
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Using Virtual Research Environments in Agro-Environmental Research
Tackling some of the grand global challenges, agro-environmental research has turned more and more into an international venture, where distributed research teams work together to solve complex research questions. Moreover, the interdisciplinary character of these challenges requires that a large diversity of different data sources and information is ...
Lokers, R.M. +4 more
openaire +2 more sources
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source

