Results 81 to 90 of about 8,158,113 (255)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

On the role of pre and post-processing in environmental data mining [PDF]

open access: yes, 2008
The quality of discovered knowledge is highly depending on data quality. Unfortunately real data use to contain noise, uncertainty, errors, redundancies or even irrelevant information.
Athanasiadis, Ioannis   +5 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Growth patterns and ecological classification of Tor tambra (Valenciennes 1842) in the Mamis River, Leuser Ecosystem Area, Aceh Province, Indonesia

open access: yesJurnal Ilmiah Perikanan dan Kelautan
Graphical Abstract Highlight Research 1. Tor tambra is the most dominant species other Tor species in Aceh Province, Indonesia. 2. The population of T. tambra has decreased significantly due to overfishing and environmental destruction.
Yusrizal Akmal   +7 more
doaj  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Semicondutores heteroestruturados: uma abordagem sobre os principais desafios para a obtenção e aplicação em processos fotoquímicos ambientais e energéticos

open access: yesQuímica Nova
Heterostructured semiconductors are materials with unique features formed by combination of two or more semiconductors with suitable interface between them.
Romero T. Bueno   +4 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

DEQ annual environmental cleanup report

open access: yes, 1992
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.3rd (Jan.

core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Ghana [PDF]

open access: yesForced Migration Review, 2008
Migration from northern Ghana is a strategy for dealing withstructural environmental scarcity rather than degradation.
Kees van der Geest, Richard de Jeu
doaj  

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