Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Environmental Accounting Disclosure Practices in Bangladesh and Its Impact on Investor Decisions [PDF]
The focus of this study is to identify the environmental disclosures made by Bangladeshi companies and analyze the overall disclosure practice of the countries’ industries.
Pizus Biswas +4 more
doaj
Konaklama Sektöründe Çevre Dostu Yönetim ve Çevre Muhasebesinin Önemi
Konaklama, turizmin en temel bileşenlerindendir. Konaklama işletmeleri çeşitli biçimlerde doğal çevreyle sürekli etkileşim içindedirler. Bu nedenle konaklama sektörü de çoğu sektörde olduğu gibi iyi yönetilmediğinde bu etkileşim sonucunda doğal çevreye ...
Semih Büyükipekçi, Şeyma Şimşek
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The Environmental Accounting: an Instrument for Promoting the Environmental Management [PDF]
Companies and managers usually believe that environmental costs are not significant tothe operation of their businesses. However, often it does not occur to them that some production costshave an environmental component.
Cleopatra Sendroiu, Aureliana Geta Roman
doaj +1 more source
Environmental Management Accounting (Ema) Sebagai Dasar Pengukuran Dampak Usaha pada Perusahaan
To determine the environmental impact, cost and benefits of it’s conservation has done, this study will be explained descriptively. It used interview and documentary techniques in obtaining data, for example raw materials data, finished products and ...
Gomal Halomoan Nainggolan +2 more
doaj
STREAMLINING CONSTRUCTION: MAXIMIZING EFFICIENCY THROUGH EFFECTIVE WASTE MANAGEMENT: THEORETICAL REVIEW [PDF]
The construction boom in Albania after the '90s had a significant impact on the country's economy. It brought about rapid urbanization, job creation, and increased investment opportunities. The construction sector became a major contributor to GDP growth,
Erjola Barbullushi, Denisa Domni
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Does Environmental Disclosure Relate to Environmental Performance? Reconciling Legitimacy Theory and Voluntary Disclosure Theory [PDF]
This paper seeks to understand the relationship between corporate environmental disclosure and corporate environmental performance in a Pakistani context.
Zeeshan Mahmood
doaj
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source

