Results 241 to 250 of about 1,232,449 (309)
Large-scale commercial-grade volatile fatty acids production from sewage sludge and food waste: A holistic environmental assessment. [PDF]
Castro-Fernandez A +5 more
europepmc +1 more source
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Performance and Environmental Assessment of Biochar-Based Membranes Synthesized from Traditional and Eco-Friendly Solvents. [PDF]
Fionah A +4 more
europepmc +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Integrated Approach for Human Wellbeing and Environmental Assessment Based on a Wearable IoT System: A Pilot Case Study in Singapore. [PDF]
Salamone F, Sibilio S, Masullo M.
europepmc +1 more source
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Solar-Powered Direct Air Capture: Techno-Economic and Environmental Assessment. [PDF]
Prats-Salvado E +3 more
europepmc +1 more source
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
Environmental assessment of PAHs through honey bee colonies - A matrix selection study. [PDF]
Murcia-Morales M +8 more
europepmc +1 more source

