Results 71 to 80 of about 746,018 (296)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Ethical Marketing: A Look on the Bright Side [PDF]
, 2006 This article offers an alternative to conventional approaches to ethical analysis in business and marketing. We submit that studying companies with exemplary records of ethical conduct and social responsibility offers useful and compelling guidance to ...
Klein, Thomas A. +2 more
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
A new approach to understanding fluid mixing in process-study models of stratified fluids [PDF]
Nonlinear Processes in GeophysicsWhile well-established energy-based methods of quantifying diapycnal mixing in process-study numerical models are often used to provide information about when mixing occurs, and how much mixing has occurred, describing how and where this mixing has taken
S. G. Hartharn-Evans +4 more
doaj +1 more source
Preliminary Study: The Influences of Environmental Management Practices and Customer Satisfaction towards Customer Loyalty [PDF]
, 2015 Green hotel is one of the efforts taken towards achieving environmental sustainability through environmental management practices applied in the hotel. However, up until November 2014, there were only 10 out of 1935 hotels registered with the Ministry of
Awang, Zainudin +2 more
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Expert Teaching Professors: Sharing Their Expertise
International Journal for the Scholarship of Teaching and Learning, 2009 The purpose of this study was to examine the processes for sharing teaching expertise used by award winning professors. The central research question of this study was: How do expert teaching professors share their expertise with mentees?
Han Shim, Gene Roth
doaj +1 more source
Reforming the public sector in the EU: the new public procurement regime [PDF]
, 2005 Commentary on the significance of the regulation of public procurement in the common market and impact on increased potential for doing business with the public sector.
Bovis, Christopher
core
Citizen Suit Attorney Fee Shifting Awards: A Critical Examination of Government-“Subsidized” Litigation [PDF]
, 1984 Silicon Carbide (SiC) is an important wide band gap semiconductor with outstanding electronic properties. With figures of merit far better than silicon, SiC is believed to replace and outcompete silicon in many applications using high frequencies, high ...
Fein, Bruce
core +2 more sources
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source