Results 81 to 90 of about 162,109 (263)
Exposed Animal Bodies: The Photographic Observation of the Body-Space of the Anthropocene
TraditionesUsing Stacy Alaimo’s theoretical concept of trans-corporeality, the paper analyzes photographs of five award-winning photojournalists, capturing various sites of exposure of animal bodies in the Anthropocene. It is not only the exposed animal bodies (i.e.
Branislava Vičar
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
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Humanities & Social Sciences CommunicationsMost architects rely on aesthetic intuition, often neglecting the mathematical foundations that underlie aesthetic judgement in design. This study addresses this gap by proposing a mathematical framework that supports both aesthetic excellence and low ...
Gangwei Cai +9 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
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Journal of Clinical and Translational ScienceObjectives/Goals: This study illuminates the efforts of a Clinical and Translational Science Award (CTSA) Hub to share stories of its aspirations, challenges, successes, opportunities, and impact when pursuing its complex goals, and how storytelling ...
Boris Volkov +1 more
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
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IUGS Recognition of the Račiška Pečina Cave section as a Global Geological Heritage Site
Acta CarsologicaRačiška Pečina, a limestone cave in the Classical karst in southwestern Slovenia, which belongs to the External Dinarides (Slovenian Cave Register No.
Nadja Zupan Hajna
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Ljubljana as a ‘Green’ and Sustainable city–Comparing and Contrasting Various Practices [PDF]
Izzivi Prihodnosti, 2017 Purpose and Originality: ‘Greenness’ and sustainability are moving from an abstract concept toward a measurable state, using the triple bottom line approach considering environmental, social, and economic dimensions.
Mihaela Rudar Neral
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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