Results 71 to 80 of about 173,357 (309)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Expert Teaching Professors: Sharing Their Expertise

open access: yesInternational Journal for the Scholarship of Teaching and Learning, 2009
The purpose of this study was to examine the processes for sharing teaching expertise used by award winning professors. The central research question of this study was: How do expert teaching professors share their expertise with mentees?
Han Shim, Gene Roth
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Green Key’s policy clarifying reference to Green Key after receiving the award [PDF]

open access: yes
This document explains what establishments having received the Green Key award must during the duration of the ...
Foundation for Environmental Education (FEE)
core  

A new approach to understanding fluid mixing in process-study models of stratified fluids [PDF]

open access: yesNonlinear Processes in Geophysics
While well-established energy-based methods of quantifying diapycnal mixing in process-study numerical models are often used to provide information about when mixing occurs, and how much mixing has occurred, describing how and where this mixing has taken
S. G. Hartharn-Evans   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Environmental public health practice in the southeastern United States : summary of environmental public health practice profiles for ten southeastern states [PDF]

open access: yes
The Federal Register for March 11, 2004, contained an announcement for \u201cRegional Academic Environmental Public Health Centers.\u201d The purpose of the announcement was \u201cto facilitate the development of an integrated national system for ...

core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Environmental products and sustainability awards

open access: yesESIC Market
Objective: To analyse the impact of companies' commitment to the production and distribution of environmental products on the winning of sustainability awards, and whether it is affected by the effects of the crisis and uncertainty caused by the Covid-19 pandemic and the Russian invasion of Ukraine.Methodology: Based on a sample of 718 companies from ...
García Sánchez, Isabel María   +3 more
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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