Results 61 to 70 of about 6,158,668 (255)

The effect of COVID-19 on the environmental impact of our lifestyles and on environmental concern

open access: yes, 2022
Since the beginning of 2020, the worldwide COVID-19 pandemic made it necessary to change our lifestyles (e.g., restrictions on transport or travelling and forced telework). This has also changed the environmental impact of our lifestyles.
Verhofstadt, Elsy   +7 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

On environmental concern, willingness to pay, and postmaterialist values: Evidence from Istanbul [PDF]

open access: yes
We explore the impact of geographical proximity of environmental problems on environmental concern and willingness to pay (WTP) for environmental improvement, with emphasis on the relevance of Inglehart’s postmaterialism thesis on this inquiry.
Gökşen, Fatoş   +2 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The Socioeconomic Determinants of Individual Environmental Concern: Evidence from Shanghai Data [PDF]

open access: yes
This study examines the influence of socioeconomic characteristics on eleven measures of environmental concern by applying a pooled sample of 1200 individuals in Shanghai, China.
Junyi Shen, Tatsuyoshi Saijo
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Environmental Concern and the Business Cycle: The Chilling Effect of Recession [PDF]

open access: yes
This paper uses three different sources of data to investigate the association between the business cycle—measured with unemployment rates—and environmental concern.
Matthew E. Kahn, Matthew J. Kotchen
core  

Environmental Sustainability in Practice

open access: yes, 2017
1. Introduction: What is Environmental Sustainability?2. Sustainability Education3. Environmental Planning and Management4. Sustainable Agriculture5. Geospatial Technologies and Environmental Sustainability6.
Environmental Sustainability Research Centre
core   +1 more source

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