Results 81 to 90 of about 8,693,539 (346)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
NAFTA and the Future of Environmental Regulation [PDF]
While NAFTA contains more "green" language than any previous trade pact, the agreement is also unprecedented in the freedom it allows investors and the extent to which it curtails government policy flexibility - important areas of concern for the ...
Perkins, Patricia E. (Ellie)
core
Infrastructural Speculations: Tactics for Designing and Interrogating Lifeworlds [PDF]
This paper introduces “infrastructural speculations,” an orientation toward speculative design that considers the complex and long-lived relationships of technologies with broader systems, beyond moments of immediate invention and design.
Bennett Cynthia L. +48 more
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Are younger people, defined by age, or younger generations, defined by cohort-level measures, more concerned about declines in environmental health when compared to their older counterparts within the United States?
S. G. Gray +3 more
semanticscholar +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
ENVIRONMENTAL CONCERN UNDER INDONESIA’S PREFERENTIAL TRADE AGREEMENTS (PTAs)
International trade has resulted positive impacts, such as alleviating poverty and increasing jobs. All countries then start concluding trade agreements multilaterally, regionally and bilaterally.
I Gusti Ngurah Parikesit Widiatedja
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
On environmental concern, willingness to pay, and postmaterialist values: Evidence from Istanbul [PDF]
We explore the impact of geographical proximity of environmental problems on environmental concern and willingness to pay (WTP) for environmental improvement, with emphasis on the relevance of Inglehart’s postmaterialism thesis on this inquiry.
Adaman, Fikret +2 more
core +1 more source

