Results 41 to 50 of about 2,180,411 (310)

Noise Costs from Road Transport

open access: yesCivil and Environmental Engineering, 2018
Building and improving road infrastructure in Slovakia is currently influenced by the amount of state funding. Therefore, it is necessary to determine the effectiveness of each proposed solution of road project, which is based on life-cycle costs ...
Margorínová Martina   +3 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Environmental cost of conservation victories [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
Ray Hilborn. In recent years, Marine Protected Areas (MPA), where fishing is severely restricted or not allowed, have become the Holy Grail of marine conservation for both nongovernmental organizations and governments. In the United States, the Papahānaumokuākea Marine National Monument in the NW Hawaiian Islands became the first large-scale reserve
openaire   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Model for Calculating Cost of Laundry Services by Considering Environmental Impacts and Costs

open access: yesJournal of Accounting and Investment, 2019
This research aims at developing a model for calculating cost of laundry services performed by small-scale laundry businesses which incorporates environmental impact and costs into the model.
Elsje Kosasih   +3 more
doaj   +1 more source

The Role of Economic Analysis in Shaping Environmental Policy [PDF]

open access: yes, 1991
The experience of the US in using economic analysis to develop environmental policy is examined. Regulatory actions needed to create environmental benefits often impose substantial costs--both direct costs and indirect effects on other social goals--so ...
Fraas, Arthur
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Diesel Buses, Oil Prices and Premature Deaths from Particulate Matter: Understanding the Connections, Exploring Solutions [PDF]

open access: yes, 2000
In 2000 the Environmental and Energy Study Institute hosted a briefing to discuss the complex issues surrounding diesel buses and alternative-fuel buses.
Randi Blank
core  

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