Results 181 to 190 of about 11,405,425 (350)

Violence and environmental crisis

open access: yesCalenda, 2020
Violence: An international journal lance un appel à contributions sur le thème « Violence et crise environnementale ». Peut-on parler de violence lorsque l'on évoque le déclin de la biodiversité, la destruction de réserves naturelles telles que l'Amazonie ou la Grande Barrière de corail, ou le déversement illégal de déchets poluants ?
openaire   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

A review of the international literature on the role of outside facilitators in the delivery of school-based sex education

open access: yes, 2009
Schools are one of the main sites where knowledge can be imparted on sexuality and relationships. There is widespread parental support in the Irish context for the provision of school-based sex education (Morgan, 2000; North Western Health Board, 2004;
Doyle, Louise   +6 more
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Improving knowledge regarding abortions performed on Irish women in the UK

open access: yes, 2007
The overall aim of this study was to provide detailed statistics on women who travel from Ireland1 to Great Britain for an abortion. This was done by using data on abortion notifications held by the Department of Health in London, plus data available ...
Clements, Steve, Ingham, Roger
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

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