Results 71 to 80 of about 162,611 (309)

Why Turn to Hegel Today? An Introduction

open access: yesEthics in Progress
This brief introduction sets the stage for the central aim of this issue of Ethics in Progress devoted to Hegel: to underscore the enduring relevance of his thought, in particular his Philosophy of Nature and his Realphilosophie, in addressing ...
Giulia Battistoni
doaj   +1 more source

Managing the Planet: The Anthropocene, Good Stewardship, and the Empty Promise of a Solution to Ecological Crisis

open access: yesSocieties, 2018
The Anthropocene has emerged as the dominant conceptualization of the current geological epoch and, more significantly, of Humanity’s relation to nature.
Charles Stubblefield
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Crisis in environmental management of the Soviet Union [PDF]

open access: yes, 1991
The prevailing system of environmental management strongly depends on the economic and political structures of a country and is influenced by the current condition of them.
Khabibullov M.
core  

Managing the environmental legitimation crisis

open access: yes, 2006
The authors discuss and extend the crisis theory of Habermas and Offe by adding and arguing for the semiautonomy of a fourth system-the ecological system. Based on Habermas\u27s crisis systems theory and J.
Marshall, Brent K., Goldstein, Warren S.
core   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Thought, Law, Rights and Action in the Age of Environmental Crisis

open access: yes, 2015
This timely book combines theoretical reflections, doctrinal analyses and insights drawn from rights-based praxis to offer thoughtful and at times provocative engagements with the limitations of law as it faces the complexities of contemporary socio ...
Grant, Evadne, Grear, Anna
core   +1 more source

Down to Earth?: A Crisis of the Environmental Crisis

open access: yes, 2023
Are we down to earth in our connection to earth? If we are environmentalists concerned with “environmental crisis,” then does our guiding notion of “environment” (and the by necessity implied notion of a center—most often with a human there) get closely enough to the earth? Departing from either localism or cosmopolitanism in thinking earth, globe, and
openaire   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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