Results 31 to 40 of about 1,410,058 (263)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Effect of Ozone Exposure on Cardiovascular and Cerebrovascular Disease Mortality in the Elderly

Toxics
Background: Ozone pollution has increased alongside China’s economic development, contributing to public health issues such as cardiovascular and cerebrovascular diseases.
Tianyun Wang, Junlong Wang, Li Sun, Ye Deng, Yuting Xiang, Yuting Wang, Jiamei Chen, Wen Peng, Yuanyao Cui, Miao He   +9 more
doaj   +1 more source

Environmental impact assessment of the manufacturing of a commercial aircraft [PDF]

, 2013
This paper documents the methodology and presents the results of a comprehensive LCA study of an Airbus A320 commercial airliner to determine the relative environmental impact of its manufacturing phase.
Asproulis, Nikolaos, Howe, Stuart, Kolios, Athanasios J., Salonitis, Konstantinos   +3 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment

Frontiers in Physiology
ObjectivePrevious research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects.
Ziqin Wei, Ziqin Wei, Hongfang Mu, Fangfang Qiu, Fangfang Qiu, Minghui Zhao, Minghui Zhao, Xiaojing Zhang, Wenbin Li, Hai Jia, Rong Wang, Rong Wang   +11 more
doaj   +1 more source

Reverse Time Migration: A Seismic Imaging Technique Applied to Synthetic Ultrasonic Data

International Journal of Geophysics, 2012
Ultrasonic echo testing is a more and more frequently used technique in civil engineering to investigate concrete building elements, to measure thickness as well as to locate and characterise built-in components or inhomogeneities.
Sabine Müller, Ernst Niederleithinger, Thomas Bohlen   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Chronic exposure to environmental concentrations of 6PPDQ induces neurotoxicity via perturbing multiple neurotransmission pathways in zebrafish

Environment International
Previous research has demonstrated acute toxicity of 6PPD-quinone (6PPDQ), the ozonation product of tire-manufacturing additive 6PPD; however, chronic effects on aquatic organisms under real-world conditions remain unclear.
Chuan Yi, Chunyan Xu, Pan Gao, Hengtao Wang, Yao Dang, Song Hou, Ruowen Zhang, Mingdeng Xiang   +7 more
doaj   +1 more source

Unlawful prosecution in the case regarding the destruction of a forest eco-system

Revista Brasileira de Direito Processual Penal, 2022
The overall complexity of the subject matter and the required high level of expertise make environmental crime investigations quite a challenging task for law enforcement.
Denis Solodov, Elżbieta Zębek
doaj   +1 more source