Results 41 to 50 of about 636,730 (266)

International Jurisdiction on Disputes of Damage Resulting from Transboundary Environmental Pollution [PDF]

open access: yesمجلة الاجتهاد للدراسات القانونية والاقتصادية, 2020
The question of environmental pollution raises many legal problems when its effects extend beyond the one state’s borders. The most apparent problem made by this issue is the International jurisdictional competence associated with the dispute of ...
Abdennour Ahmed
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Polycyclic Aromatic Hydrocarbon Pollution Stress Impairs Soil Enzyme Activity and Microbial Community

open access: yesMicroorganisms
Polycyclic aromatic hydrocarbons (PAHs) are widely prevalent harmful organic pollutants. Enzymatic activities (such as those of dehydrogenases, catalase, protease and urease), as well as the microbial community structure and assembly (through 16S and ITS
Yuancheng Wang   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Integrated Physiological, Transcriptomic, and Metabolomic Analyses Reveal the Adaptive Response of Buchloe dactyloides to Polycyclic Aromatic Hydrocarbon Stress

open access: yesPlants
Understanding how plants respond to polycyclic aromatic hydrocarbons (PAHs) stress is essential for evaluating ecological risks and improving phytoremediation strategies.
Yuancheng Wang   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Efficient degradation of methylene blue at near neutral pH based on heterogeneous Fenton-like system catalyzed by Fe2O3/MnO2

open access: yesResults in Chemistry
The contamination of aquatic environments by organic dye contaminants in industrial wastewater has attracted widespread global attention. The heterogeneous Fenton-like process presents an attractive method for degrading dye pollutants, especially when ...
Tie Geng   +9 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

IMPACT ANALYSIS OF THE 2018 TSUNAMI ON SULAWESI ISLAND USING SATELLITE IMAGERY [PDF]

open access: yesScience of Tsunami Hazards, 2021
On September 28, 2018, a strong earthquake and tsunami occurred on the island of Sulawesi (Indonesia), which turned out to be the most destructive this year (more than 2,000 people died). The magnitude of the earthquake was 7.5. Its epicenter was located
Andrey Zaytsev   +4 more
doaj  

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