Results 101 to 110 of about 519,310 (255)

Effect of Olive Pit Reinforcement in Polylactic Acid Biocomposites on Environmental Degradation. [PDF]

open access: yesMaterials (Basel), 2023
Jurado-Contreras S   +3 more
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar   +3 more
wiley   +1 more source

BETWEEN POPULATION GROWTH AND ENVIRONMENTAL DETERIORATION: THE CASE OF ZACATECAS, GUADALUPE AND FRESNILLO

open access: yesRa Ximhai, 2014
This paper documents the environmental problems of the three major urban centers of the state of Zacatecas: Fresnillo, Guadalupe and Zacatecas. These are a sample of the environmental degradation of the State, converge various topics where productive ...
Patricia Rivera-Castañeda   +1 more
doaj  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Women as Milieu Managers in Integrated Watershed Management: Perspectives from the Hilly Areas of Uttarakhand

open access: yesSpace and Culture, India, 2015
Integrated watershed management provides a viable mechanism for managing land, water and biomass of a region, especially in the rain-fed areas of India.
Dr Shyam Bahadur Singh
doaj  

The impact of green finance on environmental degradation in BRI region. [PDF]

open access: yesEnviron Dev Sustain, 2022
Chin MY, Ong SL, Ooi DB, Puah CH.
europepmc   +1 more source

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