Results 101 to 110 of about 550,045 (257)
Ra Ximhai, 2014 This paper documents the environmental problems of the three major urban centers of the state of Zacatecas: Fresnillo, Guadalupe and Zacatecas. These are a sample of the environmental degradation of the State, converge various topics where productive ...
Patricia Rivera-Castañeda +1 more
doaj
Industrialization, globalization, ICT, and environmental degradation in Malaysia: A frequency domain analysis. [PDF]
Heliyon, 2023 Ehigiamusoe KU +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Space and Culture, India, 2015 Integrated watershed management provides a viable mechanism for managing land, water and biomass of a region, especially in the rain-fed areas of India.
Dr Shyam Bahadur Singh
doaj
Effect of Olive Pit Reinforcement in Polylactic Acid Biocomposites on Environmental Degradation. [PDF]
Materials (Basel), 2023 Jurado-Contreras S +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
Does green innovation reduce environmental degradation? A panel threshold analysis for BRICS countries. [PDF]
Heliyon, 2023 Geng B +4 more
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source