Results 91 to 100 of about 1,549,315 (305)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Causes and consequences of crude oil pipeline vandalism in the Niger delta region of Nigeria: A confirmatory factor analysis approach

open access: yesCogent Economics & Finance, 2017
Significant number of crude oil pipeline vandalism in the Niger delta region of Nigeria were carried out by the militant groups on the pretext for a better environmental management and development of the region.
Ahmed Tukur Umar   +1 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Ecological attributes of the benthic community and indices of water quality in urban, rural and preserved environments Atributos ecológicos da comunidade bentônica e índices de qualidade da água de ambientes urbanos, rurais e preservados

open access: yesActa Limnologica Brasiliensia, 2012
INTRODUCTION: Reference streams are pristine streams, untouched or unaltered by man, it being possible to use their environmental characteristics as quality threshold values.
Claudia Eiko Yoshida   +1 more
doaj   +1 more source

The Environmental Kuznets Curve: a Survey of the Literature [PDF]

open access: yes
In the last few years, several studies have found an inverted-U relationship between per capita income and environmental degradation. This relationship, known as the environmental Kuznets curve (EKC), suggests that environmental degradation increases in ...
Simone Borghesi
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Analysis of Restrictive Environments in the South-West Oltenia Development Region [PDF]

open access: yesUrbanism. Arhitectura. Constructii, 2016
Restrictive environments can be defined as an area within a territorial system where development is constrained either by natural factors or anthropogenic factors.
Radu Matei Cocheci
doaj  

Preserving or escaping? On the welfare effects of environmental self-protective choices [PDF]

open access: yes
In modern societies individuals often try to alleviate their personal damages from environmental degradation by increasing their consumption of private goods. Although this “self-protective” behavior is very frequent in industrial economies, insufficient
Antoci, Angelo, Borghesi, Simone
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Bottom-to-top approach solution to environmental degradation in the Niger Delta area of Nigeria

open access: yesIanna Journal of Interdisciplinary Studies, 2023
Background: Environmental degradation in the Niger Delta Region of Niger has defiled all solutions. Therefore, there is a need to consider fresh approaches to addressing the problem.
Samuel Enudi, Ferdinand Eloke Okoro
doaj  

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